Skip to content

Artificial Intelligence in Diagnosing Dysphagia Patients

Classification of Dysphagia Patients at Risk of Aspiration Pneumonia Using Machine Learning Algorithms Incorporating Acoustic Features From Phonetic Evaluation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05098808
Enrollment
449
Registered
2021-10-28
Start date
2019-09-01
Completion date
2021-10-01
Last updated
2021-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aspiration; Liquids, Aspiration Pneumonia, Phonation Disorder, Respiration Disorders, Stroke, Swallowing Disorder

Brief summary

In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device. From these parameters we attempted (1) to define which of the PRAAT acoustic features best help to discriminate patients with dysphagia (2) to develop algorithms using sophisticated ML techniques that best classify those i) with dysphagia and those ii ) at high risk of respiratory complications due to poor cough force.

Detailed description

This study was prospective study, and patients who visited the department of rehabilitation medicine in a single university-affiliated tertiary hospital with dysphagic symptoms from September 2019 to March 2021 were included.Voice recording was performed at the enrollment with blinded assessment, where the participants first visited the rehabilitation department with chief complaints of dysphagia. The cough sounds were recorded with an iPad (Apple, Cupertino, CA, USA) through an embedded microphone. From the acoustic files we extracted fourteen voice parameters that include the average value and standard deviation of the fundamental frequency (f0), harmonic-to-noise ratio (HNR), the jitter that refers to frequency instability, and the shimmer that represents the amplitude instability of the sound signal. Machine learning algorithms and sophisticated deep neural network analysis will be performed.

Interventions

OTHERAcoustic features (from signals obtained during phonation)

Acoustic features will be obtained via phonation files. A voice recorder application provided by Apple was used, and the sampling frequency of the sound was 44,100 Hz. The digitized cough sound signals were band-pass-filtered between 20 to 16,000 Hz to use data from the whole frequency band gathered by the iPad. In each case, the smart device was positioned 20cm from the patient

Sponsors

The Catholic University of Korea
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
19 Years to 90 Years

Inclusion criteria

\- Inclusion criteria 1. Suspected swallowing disorder who were referred for swallowing assessment 2. Dysphagia attributable to brain lesion including stroke

Exclusion criteria

1. Participants who were unable to perform phonation 2. Participants who had no VFSS or standardized swallowing assessment results 3. Participants with no spirometric measurements

Design outcomes

Primary

MeasureTime frameDescription
Functional Oral Intake Scaleduring the interventionDysphagia severity as measured by the the Functional Oral Intake Scale obtained from standardized swallowing tests
Cough strengthduring the interventionSpirometry values : cough strength as measured by the spirometric values during voluntary cough

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026