Circadian Dysregulation
Conditions
Keywords
Risk: Emotional, Cognitive, Behavioral, Social, Physical
Brief summary
A follow-up of a cohort of participants recruited for a prior study will be conducted. In the prior study, 10-18 years olds were provided one of two treatments to improve the sleep of adolescent night-owls. The follow-up will be approximately 6-years following participation in the prior study. The goal is to establish long-term outcomes in sleep and circadian functioning, in the five health-relevant domains and in engagement in sleep health behavior.
Detailed description
A follow-up of a cohort of participants recruited for a prior study will be conducted. In the prior study, 10-18 years olds were provided one of two treatments to improve the sleep of adolescent night-owls. This follow-up will be conducted approximately 6-years following participation in the prior study. The participants will be 18-28 years of age. Specific Aim 1: At the 6-year follow-up, participants recruited for the prior study will be assessed for sleep and circadian functioning and functioning in five health- relevant domains. Specific Aim 2: The sample will also be assessed for their engagement in sleep health behavior. This research will advance knowledge on: (a) longer-term outcomes and (b) the role of eveningness as a mechanism contributing to poorer outcomes.
Interventions
None listed
Sponsors
University of California, Berkeley
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* The inclusion criteria is individuals who participated in a previously-funded behavioral intervention (R01HD071065).
Exclusion criteria
* N/A
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Utilization Scale | 6 years | 14-item; 0-4 scale. Scores can range from 0 to 56 (Higher score means more utilization). |
| Youth Self-Report Score for Physical Domain | 6 years | (Not a scale) A composite score of the Modifiable Activity Questionnaire and Physical Health Questionnaire will be used to assess functioning in the Social domain. |
| Youth Self-Report Score for Social Domain | 6 years | (Not a scale) A composite score of the Patient-Reported Outcomes Measurement Information System-Companionship, Patient-Reported Outcomes Measurement Information System-Emotional Support, Patient-Reported Outcomes Measurement Information System-Social Isolation, and Patient-Reported Outcomes Measurement Information System-Ability to Participate will be used to assess functioning in the Social domain. |
| Youth Self-Report Score for Behavioral Domain | 6 years | (Not a scale) A composite score of the Brief Sensation Seeking Scale, Patient-Reported Outcomes Measurement Information System -Alcohol Use, Patient-Reported Outcomes Measurement Information System-Severity of Substance Use will be used to assess functioning in the Behavioral domain |
| Youth Self-Report Score for Cognitive Domain | 6 years | (Not a scale). A composite score of the Patient-Reported Outcomes Measurement Information System -Cognitive Function and the Patient-Reported Outcomes Measurement Information System-Cognitive Function - Abilities will be used to assess functioning in the Cognitive domain |
| Youth Self-Report Composite Score for Emotional domain | 6 years | A score of Depression, Anxiety, and Stress Scale (DASS) - Sum of 21 item scale, ranging 0-3. Scores can range from 0 to 63 (Higher score means worse outcome). |
| Patient-Reported Outcomes Measurement Information System - Sleep Disturbance | 6 years | Sum of 8-items rated on a 5-point response scale. Scores can range from 8 to 40 (Higher score means more Sleep Disturbance) |
| Patient-Reported Outcomes Measurement Information System - Sleep Related Impairment | 6 years | Sum of 8-items rated on a 5-point response scale. Scores can range from 8 to 40 (Higher score means more Sleep Related impairment) |
| Composite Scale of Morningness | 6 years | Sum of 13-item; Mix of 4-point and 5-point response scale. Scores can range from 13 (extreme evening) to 55 (extreme morning). |
| Self-Report Behavioral Automaticity Index integrated with the Utilization Scale | 6 years | 14-item; 0-4 scale. Scores can range from 0 to 56 (Higher score means more automaticity in utilization). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pittsburgh Sleep Quality Index | 6 years | 19-item. First four items are integer responses. The rest of the items are on a 0-3 scale. Creates 7 composite scores, with the sum of the composite scores ranging from 0 to 21. (Higher score means increased severity of difficulty in all sleep area components). |
| Sleep Diary | 6 years | (Not a scale) Night-to-night variability in the mid-point of sleep |
| Actigraphy | 6 years | (Not a scale) Night-to-night variability in the mid-point of sleep |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Emotional Domain | 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Cognitive Domain | 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Behavioral Domain | 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Social Domain | 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Physical Domain | 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Composite Sleep Health Score | 6 years | Composite Sleep Health Score which is defined as the sum of scores on 6 sleep health dimensions: Regularity (Midpoint fluctuation), Satisfaction (Sleep quality question on PROMIS-SD), Alertness (Daytime sleepiness question on PROMIS-SRI), Timing (Mean midpoint), Efficiency (Sleep efficiency) and Duration (Total Sleep Time). The Sleep Health Composite was constructed such that higher score indicates better sleep health. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in Patient-Reported Outcomes Measurement Information System - Emotional Support | Baseline and at 6 years | Sum of 4-item; 5-point response scale. Scores can range from 4 to 20 (Higher score means higher reported emotional support). |
| Change in Patient-Reported Outcomes Measurement Information System - Social Isolation | Baseline and at 6 years | Sum of 4-item; 5-point response scale. Scores can range from 4 to 20 (Higher score means higher levels of social isolation). |
| Change in Patient-Reported Outcomes Measurement Information System - Ability to Participate in Social Roles & Activities | Baseline and at 6 years | Sum of 4-item; 5-point response scale. Scores can range from 4 to 20 (Higher score means higher ability to participate in Social Roles & Activities). |
| Change in Modifiable Activity Questionnaire | Baseline and at 6 years | 20-item. Scored by hours per week values and by Metabolic values. |
| Change in Physical Health Questionnaire | Baseline and at 6 years | Sum of 15-item, 0-2 response scale. Scores can range from 0 to 30 (Higher score means worse physical symptoms) |
| Height | Baseline and at 6 years | Centimeters (cm) |
| Weight | Baseline and at 6 years | Pounds (lbs) |
| Hip circumference | Baseline and at 6 years | Centimeters (cm) |
| Waist Circumference | Baseline and at 6 years | Centimeters (cm) |
| Change in Utilization Scale | Baseline and at 6 years | 14-item; 1-5 scale. Scores can range from 14 to 70 (Higher score means more automaticity in utilization) |
| Sleep Diary | Baseline and at 6 years | (Not a scale) Consensus sleep diary variables calculated separately for weekdays and weekends |
| Actigraphy | Baseline and at 6 years | (Not a scale) Sleep parameters will be calculated separately for weekdays and weekends |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Emotional Domain | Baseline and at 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Cognitive Domain | Baseline and at 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Behavioral Domain | Baseline and at 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Social Domain | Baseline and at 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Youth Ecological Momentary Assessment Composite Risk Score of Functioning - Physical Domain | Baseline and at 6 years | (Not a scale) Measured via Ecological Momentary Assessment |
| Alexian Brothers Urge to Self Injure Scale | 6 years | 5-item. 0-6 point scale. Total scores can range from 0-30 (Higher Score means higher Suicidal ideation) |
| Composite Sleep Health Score | Baseline and at 6 years | Composite Sleep Health Score which is defined as the sum of scores on 6 sleep health dimensions: Regularity (Midpoint fluctuation), Satisfaction (Sleep quality question on PROMIS-SD), Alertness (Daytime sleepiness question on PROMIS-SRI), Timing (Mean midpoint), Efficiency (Sleep efficiency) and Duration (Total Sleep Time). The Sleep Health Composite was constructed such that higher score indicates better sleep health. |
| Sussex-Oxford Compassion Scale (SOCS) | Baseline and at 6 years | Sum of 20-item, 5-point response scale. Scores can range from 20 to 100 (Higher score means higher compassion for self). Sub-scale items included. |
| Suicidal Behavior Questionnaire - Revised | 6 years | 4-item. Total scores can range from 3-18 (Higher Score means higher Suicidal ideation) |
| Change in Patient-Reported Outcomes Measurement Information System - Companionship | Baseline and at 6 years | Sum of 4-item; 5-point response scale. Scores can range from 4 to 20 (Higher score means higher reported companionship). |
| Change in Patient-Reported Outcomes Measurement Information System -Severity of Substance Use | Baseline and at 6 years | Sum of 7-item; 5-point response scale. Scores can range from 7 to 35 (Higher score means higher severity of substance use). |
| Change in Patient-Reported Outcomes Measurement Information System -Alcohol Use | Baseline and at 6 years | Sum of 7-item; 5-point response scale. Scores can range from 7 to 35 (Higher score means higher alcohol use). |
| Change in Brief Sensation Seeking Scale | Baseline and at 6 years | 8-item; 5-point response scale; Scores can range from 8 to 40 (Higher score means higher sensation seeking). |
| Change in Patient-Reported Outcomes Measurement Information System-Cognitive Function - Abilities | Baseline and at 6 years | Sum of 6-item; 5-point response scale. Scores can range from 6 to 30 (Higher score means higher cognitive function and abilities). |
| Change in Patient-Reported Outcomes Measurement Information System -Cognitive Function | Baseline and at 6 years | Sum of 6-item; 5-point response scale. Scores can range from 6 to 30 (Higher score means higher cognitive function ). |
| Change in Depression, Anxiety, and Stress Scale (DASS) | Baseline and at 6 years | Sum of 21 item scale, ranging 0-3. Scores can range from 0 to 63 (Higher score means worse outcome). |
| Change in Patient-Reported Outcomes Measurement Information System - Sleep Disturbance | Baseline and at 6 years | Sum of 8-items rated on a 5-point response scale. Scores can range from 8 to 40 (Higher score means more Sleep Disturbance) |
| Change in Composite Scale of Morningness (CSM) | Baseline and at 6 years | Sum of 13-item; Mix of 4-point and 5-point response scale. Scores can range from 13 (extreme evening) to 55 (extreme morning). |
| Change in Patient-Reported Outcomes Measurement Information System - Sleep Related Impairment | Baseline and at 6 years | Sum of 8-items rated on a 5-point response scale. Scores can range from 8 to 40 (Higher score means more Sleep Related impairment) |
Countries
United States
Outcome results
None listed