Cognitive Impairments in Children With Epilepsy

Interest of Speech Therapy in Children With Epilepsy: What Impairments of Cognitive Functions?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05097742

Enrollment

Registered

2021-10-28

Start date

2021-10-15

Completion date

2022-02-20

Last updated

2022-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy Syndrome

Keywords

Speech therapy, Neurology, Children, Oral language, Attention, Type of epilepsy (focal epilepsy or generalized epilepsy), Etiology of epilepsy (unknown, idiopathic, structural, metabolic, immune, infectious), Epilepsy syndrome

Brief summary

Since the proportion of language and attentional difficulties in patients with epilepsy is recognized, both in the literature and in the clinical experience of practitioners, it is appropriate to propose a complete speech-language assessment of oral language and attention.This study investigates these impairments through the taking of specific tests. The general objective of this study is to observe possible oral language and attention disorders in children with epilepsy, by age and etiology of epilepsy. The objective of this work is to study therapeutic apheresis (including plasma exchange and immunoadsorption) among french neuropediatric tertiary centers and to prove that this treatment modality is effective and well tolerated in pediatric neurology diseases.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

3 Years to 15 Years

Healthy volunteers

Yes

Inclusion criteria

The subjects should : * Be at least 3 years old and at most 15 years old * Be French speaker * Be in a regular class * Have a diagnosis of epilepsy

Exclusion criteria

* Subjects schooled in IEM * Subjects diagnosed with austim spectrum disorder * Subjects with a motor or visual handicap * Subjects with psychiatric disorders

Design outcomes

Primary

Measure	Time frame	Description
Score in the different tests assessing oral language	day 1	Test assessing oral language : * Oral naming of images * Oral designation of images * Morphosyntactic comprehension test * Syntactic production test The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : pathological zone Class 2 = 7 to 20 percentiles : fragile zone / weak zone Class 3 = 21 to 38 percentiles : low standard zone Class 4 = percentiles 39 to 62 : median standard zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : higher standard zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level.

Secondary

Measure	Time frame	Description
Score in the different tests assessing attention	day 1	Tests assessing attention : * Visual attention test * Auditive attention test The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : pathological zone Class 2 = 7 to 20 percentiles : fragile zone / weak zone Class 3 = 21 to 38 percentiles : low standard zone Class 4 = percentiles 39 to 62 : median standard zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : higher standard zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level.

Countries

France

Outcome results