Lung Health After Tuberculosis: Clinical and Functional Assessment in Post Pulmonary Tuberculosis Egyptian Patients.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05097638

Enrollment

210

Registered

2021-10-28

Start date

2018-01-20

Completion date

2020-02-04

Last updated

2021-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Function; Newborn, Abnormal, Pulmonary Tuberculoses

Keywords

pulmonary Tuberculosis, Spirometry, Pulmonary Function

Brief summary

Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment

Detailed description

Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment which may influence their quality of life. However, the pattern and nature of post-tuberculosis lung impairment is still not identified. Thus, the aim of this study was to determine the type and degree of lung physiology changes in previously treated tuberculous patients which latter may affect their quality of life; thus helping clinicians for early diagnosis of lung impairment, especially in tuberculous endemic areas.

Interventions

DIAGNOSTIC_TESTspirometry

Patient do spirometry

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patient completed an outpatient course of standard first line anti-tuberculosis therapy and declared as cured

Exclusion criteria

* Smoker (to avoid spirometry biases). * Extrapulmonary tuberculosis cases * Multidrug resistant tuberculosis * known contraindications to spirometry testing * Individuals with chest wall deformities or neuromuscular diseases * Patients who failed to achieve acceptability and reproducibility criteria of the spirometry test * Defaulter cases or irregular treatment, * known coexisting chronic lung disease as history of asthma or interstitial lung diseases * A history of illicit drug use * Patients with comorbidities: renal and hepatic insufficiency, heart diseases and metabolic disorders.

Design outcomes

Primary

Measure	Time frame	Description
Grading of obstruction function:	6 months	grading according to GOLD : mild , moderate , severe , very severe
Post tuberculosis lung functional impairment	6 months	spirometry abnormality either: restrictive, obstructive, or mixed
post tuberculosis persistent clinical symptoms	6 months	either cough , sputum , breathlessness, hemoptysis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026