Gestational Diabetes
Conditions
Keywords
Gestational diabetes, Circuit Exercise, Cognition
Brief summary
Gestational diabetes (GDM) is defined as 'pregnancy-onset or first noticed glucose intolerance'. The aim of this study is to investigate the effect of circuit exercise program applied in addition to diet therapy on cognitive function, functional exercise capacity, mobility, depression and quality of life in women with gestational diabetes. 60 female participants between the ages of 18-35 who meet the inclusion criteria will be included in the study. Participants will be randomly divided into 2 groups as diet group (n=30) and exercise group (n=30). All participants will receive GDM-specific dietary therapy for 6 weeks. In addition to diet therapy, individuals in the exercise group will be given a circuit exercise program for 6 weeks. Participants will be evaluated for blood values, cognitive status and functionality at the baseline and 6 weeks later.
Interventions
OTHERDiet
Special diet program for gestational diabetes
OTHERExercise
The circuit exercise program will consist of a medium-intensity circuit training for 50 minutes, 3 days a week, detailing the main muscle groups of the patients (chest, back, biceps, triceps, deltoid, quadriceps, thigh and calf muscles). Exercise intensity will be monitored using Borg's scale of perceived exertion, with a target intensity of 12 to 14. 8 exercises will be given in a continuous, circuit-type manner with short 1-minute rests.
Sponsors
Istanbul Medipol University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* being diagnosed with gestational DM * being between the ages of 18-35 * being in 24-32 weeks of pregnancy * being inactive physical activity level - (\<300 MET weeks/day)
Exclusion criteria
* Diagnosed with diabetes before pregnancy * have given birth before * Multiple Pregnancy (\>2) * Intrauterine growth restriction * Preeclampsia * having high risk of preterm labor and on strict bed rest * treatment with insulin or oral hypoglycemic agents during pregnancy * Other significant severe or poorly controlled medical conditions (thyroid disease, cardio-respiratory disorders, ...) * taking medications that affect cognitive function, including corticosteroids, anti-depressants, or anti-epileptics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood count test 8 | 6 weeks after baseline | Triglyceride (TG) value will be recorded. |
| Blood count test 6 | 6 weeks after baseline | Low-density lipoprotein cholesterol (LDL) value will be recorded. |
| Blood count test 7 | 6 weeks after baseline | Insulin value will be recorded. |
| Blood count test 1 | 6 weeks after baseline | Fasting blood glucose (FBG) value will be recorded. |
| Blood count test 2 | 6 weeks after baseline | Postprandial blood glucose (PBG) value will be recorded. |
| Blood count test 3 | 6 weeks after baseline | HbA1c value will be recorded. |
| Blood count test 4 | 6 weeks after baseline | Total cholesterol (T-col) value will be recorded. |
| Blood count test 5 | 6 weeks after baseline | High-density lipoprotein cholesterol (HDL) value will be recorded. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WMS Number Range Test | 6 weeks after baseline | In the forward number range, the patient is asked to repeat the numbers told to her in the same order, and in the backward number range, the patient is asked to repeat the said numbers from the end to the beginning. High scores mean a better outcome. |
| Montreal Cognitive Assessment Scale | 6 weeks after baseline | It is a screening scale developed to evaluate the early stages of cognitive impairment. Min score is 0, max score is 30. High scores mean a better outcome. |
Countries
Turkey (Türkiye)
Outcome results
None listed