Umbilical Cord of Normal Labor
Conditions
Brief summary
Human mesenchymal stem cells (MSCs) due to their regenerative and immunomodulatory properties are widely used for the treatment of bone and cartilage damage, cardiovascular, gastrointestinal, autoimmune, neurodegenerative diseases and cancer .It is shown that the use of MSCs in therapy is safe and can be effective .In 2006, the International Society for Cellular Therapy (ISCT) proposed the minimal criteria to define human MSCs. First, MSCs must be plastic-adherent when maintained in the standard culture conditions. Second MSCs must express CD105, CD73 and CD90, and lack expression of CD45, CD34, CD14 or CD11b, CD79a or CD19 and HLA-DR surface molecules.
Interventions
DEVICEflow cytomery
take sample of Wharton jelly and culturing it to know the best time for mesenchymal stem cell growth
Sponsors
Sohag University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to No maximum
Healthy volunteers
Yes
Inclusion criteria
normal babies delivered by normal labor
Exclusion criteria
diseased or congenital anomalies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| evaluation the best passage of MSC culture by CD49 surface marker | 7 months | evaluation the best passage of MSC culture by CD49 surface marker |
Countries
Egypt
Contacts
Primary Contactsamia s shawky, resident
Backup ContactHasnaa A Abo-elwafa
Outcome results
None listed