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Ultrasonographic Evaluation of Respiratory Muscles in Stroke Patients

Ultrasonographic Evaluation of Respiratory Muscles in Stroke Patients and Correlation With Pulmonary Function Tests

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05093491
Enrollment
70
Registered
2021-10-26
Start date
2020-12-25
Completion date
2022-01-28
Last updated
2022-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Function Test, Respiratory Muscle

Keywords

stroke, pulmonary function, ultrasound, respiratory muscle thickness

Brief summary

Ultrasonographic evaluation of respiratory muscle thickness in stroke patients, determination of its correlation with pulmonary function test (PFT) , and the first evaluation method to determine respiratory rehabilitation goals and to use it in the follow-up of the effectiveness of the treatment.

Detailed description

The study is planned as a cross-sectional prospective study. Healthy volunteers and stroke patients who are planned to be hospitalized in the Stroke clinic for rehabilitation in Istanbul Physical Medicine Rehabilitation Training and Research Hospital are evaluated and included in the study according to the inclusion and exclusion criteria. Demographic data of patients (gender, age, height, weight, body mass index, comorbidity status, smoking/alcohol use, dominant extremity, stroke etiology, duration, side), functional status (Brunnstrom stages, Functional Ambulation Scale (FAS), Daily Living Activity (ADL) Index), Pulmonary Function Test (PFT) measurement results and bilateral diaphragm and abdominal muscle thicknesses and thickening ratio in ultrasonography, demographic data of healthy volunteers (gender, age, height, weight, body mass index, comorbidity status, smoking/alcohol use, dominant side), PFT measurement results and the dominant side diaphragm and abdominal muscle thicknesses and thickening ratio in ultrasonography is done and included in the study. In the ultrasonographic evaluation of the participants, using a 7-12 Mhz linear Probe, measurements are made of the diaphragm at the end of tidal expiration and forced inspiration, abdominal muscles at the end of tidal expiration and at the end of forced expiration, while all respiratory muscles are lying in the supine position. Diaphragm thickness is measured between the 8th and 9th ribs at the level of the anteroaxillary line, rectus abdominis; 4 cm lateral of the umbilicus, transversus abdominis, external oblique, internal oblique muscles' measurement is made from the middle of the lowest part of the 12. rib and the highest point of the iliac crest and 2.5 cm in front of the midaxillary line. All measurements are repeated 3 times and the average value will be recorded. Vital capacity\[VC\], forced vital capacity \[FVC\], forced expiratory volume 1 second \[FEV1\] , FEV1/FVC, maximal expiratory flow rate \[PEF\], maximum inspiratory pressure \[MIP\] maximum expiratory pressure \[MEP\] in patients' PFT \] measurement results are checked. Intragroup and intergroup data are compared.

Interventions

DIAGNOSTIC_TESTSpirometry and ultrasonography in stroke group

Ultrasonographic measurements were performed of the bilateral diaphragm and abdominal muscle thickness and thickening ratio in the supine position in the stroke patient group. The spirometric evaluation was also performed

DIAGNOSTIC_TESTSpirometry and ultrasonography in healthy group

Ultrasonographic measurements were performed of dominant side diaphragm and abdominal muscle thickness and thickening ratio in the supine position in healthy individuals group. The spirometric evaluation was also performed

Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

* Ischemic or Hemorrhagic stroke patients * Stroke duration \>6 months * Mini-mental test score \>24

Exclusion criteria

* Individuals with acute or chronic lung disease * Patients with a history of thoracic or abdominal surgery * Patients with other neuromuscular diseases * Aphasia type with impaired understanding * Facial paralysis

Design outcomes

Primary

MeasureTime frameDescription
Maximum expiratory pressure [MEP]1 day (a single point in time)\>95cmH2O is normal results
FEV1/FVC1 day (a single point in time)\>%80 is normal results
Maximal expiratory flow rate [PEF]1 day (a single point in time)\>%80 is normal results
Maximum inspiratory pressure [MIP],1 day (a single point in time)\>80cmH2O is normal results
Diaphragma and Abdominal Muscle Thickness and thickening ratio1 day (a single point in time)Diaphragma and Abdominal Muscle ultrasonographic millimetric measurement
Forced vital capacity [FVC]1 day (a single point in time)\>%80 is normal results
Forced expiratory volume 1 second [FEV1]1 day (a single point in time)\>%80 is normal results

Secondary

MeasureTime frameDescription
Functional Ambulation Scale (FAS)1 day (a single point in time)min 0 max 5, bigger values mean better results,
Daily Living Activity (ADL) Index1 day (a single point in time)min 0 max 100, bigger values mean better results,
Brunnstrom stages1 day (a single point in time)min 1 max 6, bigger values mean better results,

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026