Osteosarcoma
Conditions
Brief summary
Observational retrospective cohort study using laboratory data of blood tests prior to surgical and chemotherapy treatment and other histologic, clinical, and instrumental data related to patient history from digitized medical records and analysis of the same as predictors of outcomes.
Interventions
OTHERcase series review of clinical data
Extraction of pre-surgical and chemotherapy blood test laboratory data and clinical and instrumental data related to patient history from digitized medical records and analysis
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to No maximum
Inclusion criteria
* Osteosarcoma diagnosed at the Pathological Anatomy of the Rizzoli Orthopaedic Institute in Bologna; * Minimum 2-year follow-up period; * Medical records, complete blood work and instrumental examinations, regular follow-up; * Patients with age ≥ 2 years;
Exclusion criteria
* Patients with osteosarcoma who have received medical treatment (surgery, radiotherapy or chemotherapy) in other hospitals prior to admission to our Institute
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of 5-year survival | 5 years | Evaluation of 5-year survival in relation to histologic, laboratory, clinical, and instrumental prognostic factors |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of the rate of local recurrence | 5 years | Evaluation of the rate of local recurrence and distant metastasis in relation to histological, laboratory, clinical, and instrumental prognostic factors. |
Countries
Italy
Outcome results
None listed