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Prognostic Value of IgM in Covid-19 Infection

The Prognostic Value of IgM in Covid-19 Infection

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05092594
Acronym
COVID-M
Enrollment
500
Registered
2021-10-25
Start date
2022-04-30
Completion date
2022-05-31
Last updated
2022-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Keywords

Covid-19, anti SARS-Co-V-2 IgM

Brief summary

The primary objective of the research is to study the relation between the presence and /or the anti SARS-Co-V-2 IgM level in an early stage of COVID-19 infection, and the evolution of the illness.

Detailed description

The secondary objective is to determinate in what manner response of IgM anti-SARS-Co-V-2 relates to patient's immunity statute, in regards to the other so-called humain seasonal coronavirus.

Interventions

None listed

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients ≥ 18 years; * Have been diagnosed positive of SARS-CoV-2 in the Virological Laboratory of Ambroise Paré hospital; * Have been blood sampled between 1 day and 14 days from the first clinical syndromes, and their collections of serum or plasma are conserved and accessible; * Affiliated to the social security scheme or entitled; * Informed and non-opposed to participating to the study.

Exclusion criteria

* Opposition of patient to participation to the study; * Foreign patients under french AME scheme.

Design outcomes

Primary

MeasureTime frameDescription
Hospitalizationthrough study completion, an average of 1 monthAbsence of hospitalization versus hospitalization without ventilation during SARS-CoV-2 infection
Ventilationthrough study completion, an average of 1 monthNon ventilation versus ventilation during Covid-19 hospitalization

Secondary

MeasureTime frameDescription
Oxygenotherapythrough study completion, an average of 1 monthUse of high-flow oxygenotherapy
Ventilationthrough study completion, an average of 1 monthVentilation during SARS-CoV-2 infection
IgM anti-SARS-Co-V-2 presencethrough study completion, an average of 1 monthIgM anti-SARS-Co-V-2 level
Patient's vital statutethrough study completion, an average of 1 monthDeath of hospitalized patients in Ambroise Paré hospital
Thoracic CTthrough study completion, an average of 1 monthThoracic CT result during SARS-CoV-2 infection
Hospitalization at Ambroise Paré hospitalthrough study completion, an average of 1 monthHospitalization at Ambroise Paré hospital during SARS-CoV-2 infection

Contacts

Primary ContactJean-Louis Gaillard, MD, PhD
jean-louis.gaillard@aphp.fr+ 33 (0)1 49 09 55 40

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026