Overweight and Obesity
Conditions
Keywords
Exercise therapy, Muscular strength, Resistance training, Fitness testing, Healthy lifestyle
Brief summary
The purpose of this project is two-fold: (1) to assess if two different resistance training protocols elicit different responses in the acute phase and (2) to assess if the same two different protocols will elicit different long-term responses on muscular strength, body composition and cardiometabolic health. The project will include 30 adults with obesity (defined as BMI ≥ 30 or abdominal obesity according to the International Diabetes Federation). In the acute phase blood lactate, heart rate, enjoyment and perceived exertion will be assessed after the two resistance training protocols. In addition, the mean 24-h blood glucose concentration after exercise will be compared between the two protocols. For the long-term effects blood markers of cardiometabolic health, blood pressure, body composition, objectively measured physical activity and physical fitness will be assessed before and after the intervention. Also, perceived health-related quality of life will be assessed before and after the intervention.
Interventions
OTHERModerate-repetition resistance training
Will undertake resistance training with moderate loads, and moderate repetitions 3 times per week for 7 weeks.
OTHERHigh-repetition resistance training
Will undertake resistance training with low loads, and high repetitions 3 times per week for 7 weeks.
Sponsors
Norwegian University of Science and Technology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
The study will consist of both a crossover study model (acute phase) and parallel model (chronic phase).
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Obesity (BMI ≥ 30) or * Central obesity (defined according to the International Diabetes Federation).
Exclusion criteria
* Unstable angina * recent cardiac infarction (last 4 weeks) * uncompensated heart failure * severe valvular illness * pulmonary disease * uncontrolled hypertension * kidney failure * orthopaedic/neurological limitations * cardiomyopathy * planned operations during the research period * participation in a parallel study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycated haemoglobin (HbA1c) | 7 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood lipid concentration | 7 weeks | — |
| C-reactive protein | 7 weeks | — |
| Systolic blood pressure | 7 weeks | — |
| Diastolic blood pressure | 7 weeks | — |
| Body fat | 7 weeks | Measured by bioelectrical impedance (InBody 770) |
| Fat-free mass | 7 weeks | Measured by bioelectrical impedance (InBody 770) |
| Body mass | 7 weeks | Measured by bioelectrical impedance (InBody 770) |
| Fasting glucose | 7 weeks | — |
| Waist circumference | 7 weeks | — |
| VO2max (maximal aerobic capacity) | 7 weeks | — |
| Rate of force development | 7 weeks | Measured by Kistler force plate |
| Muscular strength (1RM) | 7 weeks | Leg press and bench press |
| Muscular endurance | 7 weeks | Maximum number of repetitions using 50% of 1-RM |
| Physical activity | Baseline (before intervention), 4 and 7 weeks. | Assessed at three timepoints throughout the intervention using SenseWear armband activity monitors and/or Personal Activity IntelligenceTM (using heart rate monitors and smart phone application). |
| Health-Related Quality of Life | 7 weeks | Using the Short-Form 36 survey and Satisfaction with Physical Function and Appearance Survey |
| Visceral fat area | 7 weeks | Measured by bioelectrical impedance (InBody 770) |
Countries
Norway
Outcome results
None listed