Quadratus Lumborum Block
Conditions
Brief summary
To compare the postoperative analgesic effect of two ultrasound guided approaches of quadratus lumborum block (QLB) (anterior and intramuscular) for radical cystectomy.
Detailed description
The quadratus lumborum block (QLB) is one of the abdominal wall block techniques used to anesthetize thoracolumbar nerves . The QLB technique was described initially by Blanco et al. in 2007 (not published), then reported initially by Kadam in 2013. Since then, QLB has evolved with the development of the ultrasound-guided nerve block. To date, several randomized controlled trials have reported effective postoperative analgesia, with non-intramuscular QLB for cesarean sections, laparoscopic gynecologic surgery and hip hemiarthroplasty . The intramuscular QLB (QLBi) technique was first reported by. This approach is different from others in tubouchi for QLB; although the injection target sites of the other approaches are planes around the quadratus lumborum muscle, the intramuscular approach penetrates the fascia of the quadratus lumborum muscle, where local anesthetics are injected. Therefore, QLBi is relatively easier to perform compared with other QLB approaches. The incidence of urinary bladder cancer in the Middle East and Africa is greater in areas with high rather than low SH prevalence.
Interventions
PROCEDUREUS guided injection
using 2.5mg/kg of 0.25% bupivacaine diluted in a 20 mL syringe of normal saline , received ultrasound-guided quadratus lumborum.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age: 40-70years. * BMI: 20-30 kg.m2 * Sex: both males and females. * American Society of Anesthesiologists (ASA )physical status: I-III. * Operation: radical cystectomy
Exclusion criteria
* • Patient's refusal to participate in the study. * known allergy to local anesthesia (LA), * coagulopathy or thrombocytopenia, * body mass index (BMI) above 30 kg .m 2, and infection at site of injection. * Chronic pain syndromes, * Prolonged opioid medication, * Patients on regular use of analgesic or who received analgesic 24 h before surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate the first call for rescue analgesia | 24hours after recovery From anesthesia | The time of the first call of analgesia is recorded |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total doses of morphine required | 24hours after recovery from anesthesia | Doses of morphine required postoperative |
Countries
Egypt
Contacts
Primary ContactHassan Mostafa abdelbaky ahmed, Master
Backup ContactAbdel raheem Mahmoud Mohamed, Prof
Outcome results
None listed