Evaluation of Flexofytol® PLUS in Hand Joint Chronic Dyscomfort.

Curcuminoids and Boswellia Serrata Extracts Combination Decreases Hand Joint Discomfort : Results From a Belgian Real-Life Experience

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05089318

Enrollment

239

Registered

2021-10-22

Start date

2019-09-01

Completion date

2021-09-01

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Joint Discomfort

Keywords

Hand joint pain, curcumin, boswellia serrata, support to standard treatment

Brief summary

The purpose of this study is to evaluate the effect of curcuminoids and Boswellia serrata extracts combination (Flexofytol PLUS) in support to standard treatments during a 12-weeks period on hand pain on people with chronic hand joint discomfort.

Interventions

DIETARY_SUPPLEMENTFlexofytol PLUS

2 tablets in the morning and in the evening for minimum 6 weeks.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* Older dan 45 years old, * With hand joint chronic discomfort, * Regularly uses of paracetamol or NSAIDs to manage pain, * Painful symptoms must have been present for more than 6 months, * The patient assesses their pain on a visual pain scale and must be greater than 4 out of 10 over the last 48 hours.

Exclusion criteria

* Related to previous and associated treatments: * Corticosteroids injection in the 3 previous months, whatever the joint concerned, * Use of Slow-acting drugs for OA and/or dietary supplements taken within less than 6 months prior to the study (ex: chondroitin sulfate, diacerein, soy and avocado unsaponifiables, oxaceprol, granions de cuivre, glucosamine, phytotherapy or homeopathy for hand joint discomfort..), * Anticoagulant (coumarinic) treatment and heparin, * General corticotherapy in the 3 previous months, * Contraindication to paracetamol, curcumin, boswellia and NSAID's. * Related to associated pathologies: * Patient suffering from serious associated illness (liver failure, kidney failure, non-controlled cardiovascular diseases...), * The patient has rheumatoid arthritis or gout, * The patient has a bile obstruction. * Related to patient: * Pregnant or breastfeeding women.

Design outcomes

Primary

Measure	Time frame	Description
Pain using a Numerical Rating Scale (NRS)	84 days	Change from baseline of the mean pain over the last 48 hours evaluated by the patient on a 0 to 10 scale ( 0= no pain and 10=maximal pain)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026