GLIM-defined Malnutrition Criteria for Postoperative Outcomes in Patients With Esophagogastric Cancer

The Application Value of Preoperative Fat-free Mass Index Within GLIM-defined Malnutrition Criteria for Postoperative Outcomes in Patients With Esophagogastric Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05088304

Enrollment

205

Registered

2021-10-21

Start date

2015-09-01

Completion date

2018-07-01

Last updated

2021-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer of Esophagus, Cancer of Stomach, Malnutrition, Muscle Loss

Keywords

FFIM, GLIM, Cancer, Postoperative complications

Brief summary

The present study aims to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the Global Leadership Initiative on Malnutrition (GLIM) criteria.

Detailed description

The GLIM criteria of malnutrition as a consensus lack of optimal combination in clinical validation. After the publication of the GLIM consensus, few studies have examined the effect of reduced FFMI on the clinical prognosis of patients with esophagogastric cancer, and whether the FFMI can be used as an effective diagnostic criterion of malnutrition in esophagogastric cancer needs to be further studied. Therefore, the present study aims were to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the GLIM consensus for malnutrition.

Interventions

OTHERno intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Elective surgery for esophagogastric cancer (there was a clear pathological diagnosis before surgery); NRS2002≥3; Preoperative BIA examination was performed.

Exclusion criteria

Discharged from a hospital within 24 hours; No BIA examination and not suitable for BIA examination (such as ascites, edema, amputation and pace-maker); Hepatic insufficiency (alanine transaminase/aspartate transaminase ratio 200% above normal range or bilirubin\>3mg/dL) ; Renal insufficiency (serum creatinine\>1.5mg/dL); Emergency operation; Pregnancy; Missing the postoperative information follow-up data.

Design outcomes

Primary

Measure	Time frame	Description
postoperative complications	Within 60 days after surgery	postoperative complications (infectious complications and noninfectious complications)

Secondary

Measure	Time frame	Description
hospitalization cost	Within 60 days after surgery	hospitalization cost(including: surgery and medicine costs)
wound healing time	Within 60 days after surgery	wound healing time
postoperative antibiotic time	Within 60 days after surgery	postoperative antibiotic time
nutritional status	up to 4 weeks	nutritional status ( such as: weight，albumin，prealbumin)
length of stay (LOS)	Within 60 days after surgery	length of stay (LOS)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026