Anti-Infectives Adverse Reaction, Breast Cancer, Infections, Perforator Flap
Conditions
Keywords
Prophylatic antibiotics, DIEP flap
Brief summary
Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy. We try to standardize prophylactic antibiotics use during breast reconstruction with deep inferior epigastric perforator flap following mastectomy. Methods: This retrospective case series involved 108 patients who underwent immediate breast reconstruction with deep inferior epigastric perforator flap in Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019. Patients were divided into three groups based on prophylactic antibiotic duration: 1 day, 3 days and \>7 days for patients with drains Data were analyzed between January and April, 2021.
Interventions
DRUGprophylactic antibiotics duration
Prophylactic cefazolin 1000 mg was given 30 minutes before surgery, every 4 hours in the peri-operative period, and every 6 hours in the post-operative care. Different discontinued duration of antibiotics was divided to 3 groups in one day, 3 days and until to drain removal.
Sponsors
Chiayi Christian Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
24 Years to 63 Years
Healthy volunteers
No
Inclusion criteria
* This retrospective study involved 108 patients who underwent immediate DIEP flap breast reconstruction after unilateral or bilateral mastectomy at the Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019.
Exclusion criteria
* Age \< 20 years old.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| surgical site infection (SSI) | Patients were then followed up in the outpatient department for 1 year. | Infection rate of surgical wounds of breast and abdomen. |
Outcome results
None listed