COVID-19
Conditions
Brief summary
retrospective cohort (non-experimental study) of COVID 19 patients assisted in hospitalization (severe and critical) between 2020 and 2021
Detailed description
Consecutive patients with acute infection by SARS-COV2 and severe or critical COVID19 disease, or acute complications, hospitalized in the Pasteur Clinic of Neuquén city from the beginning of the pandemic in the region until December 31, 2021. Data were obtained retrospectively from information registered simultaneously with hospitalization in three databases (RedCap, DataTech and Excel). . Inclusion criteria * Adult patients (over 18 years old) * Suffering from acute infection by SARS-Cov2, diagnosed by PCR-real time, detection of viral antigen, specific antibodies with or clinical epidemiological criteria * Hospitalized defined by attending physicians or referral (severe or critical according to NIH) Exclusion criteria * Patients under 18 years of age. * Convalescent from acute SARS-Cov2 infection and without evidence of a new event of reinfection. * Outpatient management or hospitalization less than 24 hours for diagnosis and / or evaluation of severity or complications. Sample Selection Method First patient was registered at the beginning of the pandemic in the region March 20, 2020) and is expected to recruit the las patient diagnosed in December 31, 2021. The recruitment is consecutive without other selection criteria.
Interventions
OTHERComorbidities
Risk factors (comorbidities), requirements of respiratory suppot and chest imaging will are considered exposure for primary outcomes
Sponsors
Asociacion Latinoamericana de Torax
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adult patients (over 18 years old) * Suffering from acute infection by SARS-Cov2, diagnosed by PCR-real time, detection of viral antigen, specific antibodies with or clinical epidemiological criteria * Hospitalization defined by attending or referral physician (severe or critical according to NIH)
Exclusion criteria
* Patients under 18 years of age. * Convalescent from acute SARS-Cov2 infection and without evidence of a new event reinfection. * Outpatient management or hospitalization less than 24 hours for diagnosis and / or evaluation of severity or complications.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 28-day mortality | From date of admition until the date of death from any cause, assessed up to 28 day | defined as death ocurred within 28 days of admition to hospital |
| Hospital mortality | From date of admition until the date of death from any cause, assessed up to 52 weeks | defined as death ocurred within hospitalization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Invasive Mechanical ventilation | From date of admition until the date of equirement of invasive mechanical ventilation, assessed up to 21 day | defined as requirement of invasive mechanical ventilation support |
Countries
Argentina
Outcome results
None listed