Colorectal Cancer, Surgery
Conditions
Brief summary
This study aims to establish a colorectal cancer cohort, collect clinicopathological information, collect biological samples for multi-omics testing, and perform relevant analysis, to predict the prognosis of colorectal cancer, guide the diagnosis and treatment of colorectal cancer and the formulation of health policies.
Detailed description
In this study, the investigators will establish a database to collect clinical pathological information, based on the medical data system of participating medical centers. The investigators will also collect corresponding tumor specimens and perform multiple omics tests such as genome, transcriptome, and proteome. The investigators will aggregate these data into a special database, and use appropriate methods to conduct big data analysis, to predict prognosis, guide diagnosis and treatment, and assist in formulating health policies.
Interventions
PROCEDUREcolorectal cancer surgery
Any surgery for primary tumor of colorectal cancer, including palliative resection, simple bowel stoma and exploratory surgery.
Sponsors
Fudan University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Pathologically diagnosed as colorectal cancer * Receiving any surgery of primary tumor, including palliative resection, simple enterostomy and exploratory surgery
Exclusion criteria
* The patient refused to join the study * The patient refused to collect the biological sample * The patient refused to follow up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Disease-free survival time | 2 yeas after surgery | For patients received radical resection of colorectal cancer, disease-free survival time is defined as time from the surgery to any recurrence of disease or death, recorded in months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival time | 2 yeas after surgery | Overall survival time is defined as time from the surgery to death, recorded in months. |
| Pathological TNM stage | 1 month after surgery | The pathological TNM stage included the pathological T stage, pathological N stage and M stage. The pathological T and N stage is decided according to the removed specimen of the primary tumor by the pathologist after surgery. The M stage is decided according to the imaging tests as CT, MRI and PET-CT. |
Countries
China
Contacts
Primary ContactJianmin Xu, Prof.
Backup ContactQingyang Feng, Dr.
Outcome results
None listed