Cardiovascular Complication, Influenza
Conditions
Brief summary
"Influenza and the Heart: An investigation into the acute and lasting cardiac effects of influenza infection" the investigators aim to assess the mechanisms for cardiovascular disease in patients suffering an acute influenza infection. The project will be carried out by creating a prospective clinical cohort study of consecutive patients hospitalized at Herlev & Gentofte University Hospital with a laboratory confirmed influenza.
Interventions
None listed
Sponsors
University Hospital, Gentofte, Copenhagen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* All patients hospitalized at Herlev \& Gentofte University Hospital with a laboratory-confirmed diagnosis of influenza * \> 18 years of age
Exclusion criteria
* Persons not able to cooperate * Persons unable to understand and sign "informed consent" * Pregnancy * Persons simultaneously positive with COVID-19
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients developing cardiovascular complications | 3 years | Including new-onset heart failure, worsening of current heart failure, acute myocardial infarction, and cardiac arrest |
| Number of patients developing in-hospital mortality | 3 years | — |
| Rate of cardiac dysfunction | 3 years | Defined by impaired echocardiographic parameters and elevated cardiac biomarkers - NT \- pro \- BNP annd hs \- TNT |
| Prevalence of elevated biomarkers of infection/inflammation | 3 years | Prevalence of elevated biomarkers of infection/inflammation and it association with cardiac dysfunction |
| Rate of pulmonary embolisms diagnosed with CT thorax angiography | 3 years | — |
Countries
Denmark
Outcome results
None listed