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Mirror Illusion Training and Cross-education

Mirror Illusion Training to Improve Contralateral Arm Strength

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05084690
Enrollment
20
Registered
2021-10-20
Start date
2021-07-19
Completion date
2023-08-19
Last updated
2021-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Therapy, Weight Lifting

Keywords

Strength training, Mirror visual feedback

Brief summary

Cross-education describes the transfer of motor performance to the opposite limb following unilateral training and is primarily explained by adaptations within the brain. The mirror training hypothesis suggests that illusionary mirror visual feedback may augment the cross-education of strength to the untrained, contralateral limb. The purpose of this project is to examine how the use of illusionary mirror visual feedback shapes the neuromuscular adaptations that occur for both limbs during unilateral (single-limb) strength training. Our hypothesis is that mirror training will augment the level of cross-education for the untrained arm.

Detailed description

Recent empirical evidence shows a heightened level of strength transfer with the use of illusionary mirror visual feedback, but this was shown for the small muscles of the wrist during isokinetic training. It is unknown if larger, multi-joint muscles respond favorably to mirror training in practical settings. A randomized controlled study design will allocate approximately 20 participants into two groups. One group will perform unilateral strength training with illusionary mirror visual feedback (Mirror) and the other will perform the same unilateral strength training but without a mirror (No-Mirror). The intervention will involve four weeks of unilateral strength training performed twice weekly at high intensities (\>80%1RM).

Interventions

Unilateral resistance training of the elbow flexors

OTHERIllusionary mirror visual feedback

Modified Ramachandran's mirror box

Sponsors

Texas Christian University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)

Intervention model description

Randomized, two arm parallel experimental and control groups

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* right-hand dominance * no previous strength training of upper body last 3 months * no injuries or recent surgeries of the upper limbs * willingness to adhere to the strength training requirements of the study

Exclusion criteria

* current use of hormone replacement therapy * pregnancy/breastfeeding

Design outcomes

Primary

MeasureTime frameDescription
Change in dynamic muscle strength for the trained and untrained armBaseline (week 0) post-training (week 5)Dynamic 1-repetition maximum (lbs)
Change in isometric muscle strength for the trained and untrained armBaseline (week 0) post-training (week 5)Isometric maximal voluntary contraction
Change in lean mass for the trained and untrained armBaseline (week 0), mid-training (week 2), post-training (week 5)DEXA (g)
Change in muscle thickness for the trained and untrained armBaseline (week 0), mid-training (week 2), post-training (week 5)Ultrasound muscle thickness (cm)
Change in muscle activation for the trained and untrained armBaseline (week 0) post-training (week 5)Electromyographic amplitude (volts)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026