Other Skin and Subcutaneous Infections
Conditions
Brief summary
This randomized, placebo-controlled, double-blind, and cross-over study was designed to check whether the roselle-based drink (2 bottles every day) can alter blood pressure and skin condition in elderly healthy subjects.
Detailed description
The subjects were assigned into two groups (control group and test group), each group subject was requested to drink 2 bottles every day (100 mL/bottle, one in the morning and another in the evening), the rate of drinking is 75.42%. There are 39 subjects (25 females and 14 males) completely involved in the thirteen-month trial (cross-over). Blood samples were collected at the initial, 3rd, 6th, 7th, 10th, 13th months of the trial. Skin examinations were performed at the initial, 6th, 7th, 13th months.
Interventions
DIETARY_SUPPLEMENTDrink
Roselle and placebo drink for 6 months
Sponsors
Chung Shan Medical University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 81 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults * Subjects should not be under any medication * Subject must be able to drink
Exclusion criteria
* Subjects with chronic renal, liver or cardiac disorders, Diabetes, hyperlipidemia. * Also pregnant women, chain smokers, high alcohol consumers should not be included.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure by sphygmomanometer (mmHg) | 6 months | Both systolic and diastolic blood pressure were changed after Roselle drink |
Countries
Taiwan
Outcome results
None listed