Traumatic Brain Injury
Conditions
Brief summary
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.
Interventions
None listed
Sponsors
University of Maryland, Baltimore
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 79 Years
Inclusion criteria
* Arrival to the hospital within 6 hours of injury * Age \>= 18 years old * Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings.
Exclusion criteria
* Deemed to have a non-survivable TBI * Brain dead on arrival * Active substance abuse for opiates and cocaine as noted by admission toxicology screen. * Any thoracic or abdominal injury resulting in open surgical intervention * Pregnancy * Prisoners * Active military * Non - English speaking (due to necessity for consent in aims 2 and 3) * Age \> 89 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neurological Decline | First 48 hours of injury | Neurological decline is defined as a worsening in neurological status determined by a 2 point decline GCS, pupillary change, radiographic worsening defined by Rotterdam score, need for neurological or neurosurgical intervention (eg. treatment of seizure, raised ICP, hematoma evacuation) |
Countries
United States
Outcome results
None listed