Covid19
Conditions
Brief summary
1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2. investigate the factors on antibody titer.
Detailed description
1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 1) semi-quantitative measurement of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2) investigate the duration maintaining acceptable range (over 30% inhibition) 2. investigate the factors on antibody titer at 2 month after vaccination 1) potential factors: age, sex, body weight, height, use of medication, use of antipyretics (NSAID or tyrenol), side effect of COVID-19 vaccination 2) correlation between antibody titer and potential factors 3. Compare 4 diagnostic ELISA kit at 2 month after vaccination 1) measure neutralizung antibody using ELISA kits from 4 different companies 2) investigate correlation coefficient of antibody titer between companies
Interventions
DIAGNOSTIC_TESTCOVID-19 neutralizing antibody
This study enrolled persons already who received COVID-19 vaccination under government policy. 1. We collect 5mL blood at 2, 4, 6, 9, 12 months after COVID-19 vaccination 2. isolate serum and store in -80 degree deep freezer 3. measure neutralizing Antibody
Sponsors
Kyungpook National University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Inclusion criteria
* healthcare works after completion of COVID-19 vaccination * 20-60 years * sign the agreement of study
Exclusion criteria
* serious underlying diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| titer of neutralizing antibody after COVID-19 vaccination | at 2month after COVID-19 vaccination | semi-quantitative measurement of neutralizing antibody after COVID-19 vaccination |
| body weight (Kg) | at 2 month after COVID-19 vaccination | correlation between antibody titer and body weight: spearmann's correlation |
| body mass index (kg/m^2) | at 2 month after COVID-19 vaccination | correlation between antibody titer and body weight: spearmann's correlation |
| Compare 4 diagnostic ELISA kit after COVID-19 vaccination | at 2 month after COVID-19 vaccination | 1. measure neutralizung antibody using ELISA kits from 4 different companies 2 months after COVID-19 vaccination 2. investigate correlation coefficient of antibody titer between companies |
Countries
South Korea
Contacts
Primary ContactSu Youn Nam, MD, PhD
Outcome results
None listed