Achalasia, GERD
Conditions
Keywords
Peroral endoscopic myotomy, High-resolution esophageal manometry
Brief summary
Achalasia is an uncommon disorder that results from the degeneration of ganglion cells of the myenteric plexus in the lower esophageal wall. Peroral endoscopic myotomy (POEM) is a minimally invasive procedure capable of overcoming limitations of achalasia treatments. This study aimed to: 1) identify the prevalence of reflux esophagitis and asymptomatic GERD in patients who underwent POEM, and 2) evaluate patient and intraprocedural variables associated with post-POEM GERD.
Interventions
OTHERPatients who underwent POEM
chalasia patients were recruited from a single center. The pre- and postoperative assessments included Eckardt scores, GerdQ questionnaire, high-resolution esophageal manometry, esophagogastroscopy and pH monitoring.
Sponsors
Maria Sklodowska-Curie National Research Institute of Oncology
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Males and females who are 18 years of age and older and are willing to sign an Informed Consent Form (ICF) 2. Achalasia patients who underwent POEM
Exclusion criteria
1. Lack of written consent for participation in the study 2. Conditions which are contraindication to Esophagogastroscopy and High-resolution Esophageal Manometry
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence of gastroesophageal reflux after peroral endoscopic myotomy (POEM) | 36 Months |
Countries
Poland
Contacts
Primary ContactAnna Chaber-Ciopińska, PhD
Backup ContactAleksandra Budnicka-Borkowicz, MD
Outcome results
None listed