Rectal Cancer
Conditions
Brief summary
Even after adequate TME with grade III mesorectal grading, local recurrence remains a possible event. Several studies investigated different parameters and assessed their predictive power in regards to local recurrence after TME. These parameters included a variety of patient-related, tumor-related, and treatment-related factors. A recent meta-analysis reviewed the current literature for the predictors of local recurrence after TME for rectal cancer and developed a prognostic scoring system, the PREDICT score. The present study aimed to validate the PREDICT scoring system by applying it to a prospective cohort of patients with rectal cancer who underwent curative TME in three
Interventions
DIAGNOSTIC_TESTPREDICT score
Predictive score for local recurrence after TME for rectal cancer that includes 8 parameters
Sponsors
Mansoura University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients of either sex with non-metastatic low or middle rectal cancer who underwent elective TME with curative intent
Exclusion criteria
* Patients with recurrent or metastatic rectal cancer at the time of presentation * Patients with synchronous colon cancer * Patients with missing data on the outcome of TME.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sensitivity of PREDICT score | 36 months after surgery | The ability of the score to predict actual cases of recurrence after TME |
| Specificity of PREDICT score | 36 months after surgery | The ability of the score to predict patients who did not experience recurrence after TME |
Countries
Egypt
Outcome results
None listed