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Temporomandibular Joint and COVID-19

Temporomandibular Joint Complains in Patients With COVID-19

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05077189
Enrollment
76
Registered
2021-10-14
Start date
2020-12-01
Completion date
2021-06-01
Last updated
2021-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ASA Triad, COVID-19, Temporomandibular Disorder

Keywords

coronavirus, TMJ disorder, DC/TMD, ASA, Sars-CoV-2

Brief summary

There is evidence that CV-19 is associated with joint symptoms, but there are no specific data on the temporomandibular joint (TMJ). It is also known that the systemic health status can impact the immune system. Given all this, this study aimed to investigate the effect of CV-19 and systemic health status, as determined by the American Society of Anesthesiologists (ASA) Physical Status Classification System 12, on TMJ in patients with TMJ complaints using the DC/TMD scale.

Detailed description

This study investigates the effect of systemic status, according to American Society of Anesthesiologist (ASA), and COVID-19 on temporomandibular joint (TMJ) disorders using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) scale, shown to be valid for assessing TMJ disorders. The study included 76 patients who presented to our clinic with TMJ. Participants were divided into two groups: those with COVID-19 (CV-19, study group) and those without (non-CV-19, control group). These two groups were both further divided into subgroups according to ASA 1 and ASA 2 classification. Power analyses were performed using G\*Power software to determine the required number of patients. Groups were compared using the Symptom Questionnaire, a demographics survey, the Graded Chronic Pain Scale (GCPS), and the Jaw Functional Limitation Scale-20 (JFLS-20) of the DC/TMD. The statistical software program version 1.6.23 was used for statistical analysis. Although joint complaints were more common in ASA 2 patients with CV-19, the groups were not significantly different. The CV-19 ASA 2 group had the highest JFLS-20 score (mean: 1.3±1.5) and the non-CV-19 ASA 1 group had the lowest JFLS-20 score (mean: 0.7±0.8), but the differences were again not significant. Joint complaints were more common and more severe in ASA 2 patients with CV-19, albeit not with statistical significance. More studies are needed to better understand our results.

Interventions

OTHERDiagnostic Criteria for Temporomandibular Disorders (DC/TMD) scale

4 items of the DC/TMD scale were used in this study to evaluate the TMJ disorders. 1. Demographics Survey 2. DC/TMD Symptom Questionnaire (SQ) 3. Graded Chronic Pain Scale (GCPS) 4. Jaw Functional Limitation Scale-20 (JFLS-20)

Sponsors

Recep Tayyip Erdogan University Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* applied to our clinic with TMJ discomfort * ASA 1 and ASA 2 patients

Exclusion criteria

* patients with acute CV-19 * Patients who are not in ASA 1 or ASA 2 classification * Patients under 18 year-old * Pregnants

Design outcomes

Primary

MeasureTime frameDescription
DC/TMD scale - Demographics Surveythrough study completion an average of 3 monthsThis survey consisted of 6 items concerning marital status, socioeconomic status, profession, education, and children.
DC/TMD scale - DC/TMD Symptom Questionnairethrough study completion an average of 3 monthsThis 14-item questionnaire aims to determine the duration and causes of pain and the associated symptoms.
DC/TMD scale - Graded Chronic Pain Scalethrough study completion an average of 3 monthsThis 8-item scale is graded on a scale of 0-10 points. It includes 3 questions on pain intensity, 4 questions on function, and 1 question on the number of days with facial pain. The GCPS consists of two subscales. As the first subscale, Characteristic Pain Intensity is measured, where a score of ≥50 out of 100 possible points indicates high-intensity pain. The Interference Score is then calculated as the second subscale based on scores concerning interference in daily activities and work and the number of days with interference
DC/TMD scale - Jaw Functional Limitation Scale-20through study completion an average of 3 monthsThis scale consists of three subscales that address limitations of mastication, vertical mobility, and verbal and non-verbal communication. These three subscales are ideal for both research purposes and patient assessment of various functional limitations of the jaw. It is a global scale that consists of 20 items and the three aforementioned subscales (mastication, vertical mobility, and verbal and non-verbal communication)

Secondary

MeasureTime frameDescription
ASA 1through study completion an average of 3 monthsAmerican Society of Anesthesiologist 1 - systemically healthy patients
ASA 2through study completion an average of 3 monthsAmerican Society of Anesthesiologist 2 - A patient with mild systemic disease

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026