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Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia

Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05076929
Enrollment
60
Registered
2021-10-13
Start date
2021-05-28
Completion date
2022-03-01
Last updated
2022-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Hypovolemia, Cerebrospinal

Brief summary

Administration of intravascular fluids is one of the methods to prevent SA-induced hypotension, but empirical intraoperative volume repletion carries the risk of fluid overload during elective surgery. Over fluid resuscitation is associated with organ dysfunction and higher mortality rate , thus, to avoid ineffective or even harmful intravascular volume expansion, it is important to have tools to predict hypotension and fluid responsiveness.

Interventions

DIAGNOSTIC_TESTultrasound

Ultrasonographic measurement of Inferior Vena Cava Collapsibility Index

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* ASA grade I, II, III * Age 18 -65 yrs * Spinal Anesthesia

Exclusion criteria

* Patient refusal * Patient having contraindication of Spinal Anesthesia (infection at the site of injection, spine deformity, coagulation disorders ) . * Known cardiac, renal, neurological, metabolic, endocrine, psychiatric, respiratory disease.

Design outcomes

Primary

MeasureTime frame
mean arterial blood pressure15 minutes after tourniquet release

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026