Psoriasis
Conditions
Keywords
psoriasis, metabolic syndrome, interleukin 38
Brief summary
case control study to compare level of interleukin 38 in patients with psoriasis and patients with metabolic syndrome with healthy control subjects
Detailed description
this case control study will measure plasma level of interleukin 38 in 4 groups of 24 subject, group one will have psoriatic patients, group 2 will have psoriatic patients with metabolic syndrome, group three will have patients with metabolic syndrome only, and group 4 will have healthy control subjects.
Interventions
DIAGNOSTIC_TESTmeasure plasma level of interleukin 38 by ELISA kit
draw 5 ml of venous blood into EDTA tubes and centrifuged then plasma is separated for test
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* specific to each group
Exclusion criteria
* Patient refusal. Age \<18 years Pregnancy Lactation smoking Infections. Patients with other inflammatory skin disorders use of antioxidant and anti-inflammatory drugs patients on treatment for psoriasis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure plasma level of interleukin 38 in all groups | through study completion an average of 18 months | level of interleukin 38 will be measured and compared in all groups to asses the relationship between this interleukin and metabolic syndrome in psoriatic patients |
Contacts
Primary ContactYomna A Abdellatif, MBBCH
Backup Contactwafaa m abdel-magid, asst prof
Outcome results
None listed