Cesarean Section Complications
Conditions
Brief summary
In hypertensive women having an elective cesarean section, the effectiveness and safety of temporary uterine packing coupled with topical tranexamic acid as an adjuvant for decreasing blood loss during delivery were compared to placebo.
Detailed description
patients were allocated to one of two groups after induction of anesthesia. they received temporary uterine packing with gauze of the dimensions soaked with 2 gm tranexamic diluted in 60ml saline acid or placebo
Interventions
temporary uterine packing with gauze of the dimensions soaked with 2 gm tranexamic diluted in 60ml saline acid
OTHER: normal saline
temporary uterine packing with gauze of the dimensions soaked with placebo to 2 gm tranexamic diluted in 60ml saline acid
Sponsors
Aswan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
a double-blinded randomized controlled trial
Intervention model description
a double-blinded randomized controlled trial
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* hypertensive women undergoing elective cesarean section
Exclusion criteria
* Patients with cardiac, hepatic, renal, or thromboembolic disease. , * patients with the high possibility of the morbid adherent placenta, * known coagulopathy and * those presented with severe antepartum hemorrhage * refuse to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| intraoperative blood loss | 30 minutes | measures the intraoperative blood loss by direct and gravimetric methods |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| need of blood transfusion | 12 hours | number of unites of blood transfusion |
| need of uterotonic | 24 hours | misoprostol, oxytocin etc |
| change in hemoglobin | 24 hours | change in hemoglobin |
Outcome results
None listed