Cystoid Macular Edema
Conditions
Keywords
cystoid macular edema, rhegmatogenous retinal detachment, vitrectomy, gas tamponade
Brief summary
To investigate the incidence of cystoid macular edema in eyes with primary rhegmatogenous retinal detachment successfully treated with vitrectomy with gas tamponade, and to evaluate the clinical variables associated with its development.
Detailed description
this is an observational, retrospective, multicentre study. The study is based on the retrospective collection of clinical data from patients undergoing gas tamponade vitrectomy for rhegmatogenous retinal detachment. The collection of such data by the investigators will take place at each participating center anonymously. demographics, systemic, and preoperative, intraoperative and post-operative data will be collected The sample size was calculated to obtain approximately 200 patients with cystoid macular edema. Since cystoid macular edema has been detected in 13% of patients after retinal detachment gas vitrectomy, and assuming that this event can occur between 10% and 15% of cases, the study will include at least 2000 cases.
Interventions
PROCEDUREvitrectomy
vitrectomy with gas tamponade
Sponsors
University of Catania
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* primary rhegmatogenous retinal detachment treated with vitrectomy with gas tamponade; * follow-up of 3 months or more; * age \> 18 years ; * no previous eye surgery, except cataract surgery performed at least 6 months after hospitalization for retinal detachment; * anatomical success, i.e. retinal re-attachment, after a single gas vitrectomy; * no other eye surgery during follow-up; * availability of optical coherence tomography (OCT) imaging
Exclusion criteria
* history of other eye diseases (glaucoma, age-related macular degeneration, uveitis, diabetic retinopathy, maculopathy); * macular hole; * recurrent retinal detachment; * use of silicone oil is used as a tamponading agent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of cystoid macular edema | from 1 month up to 6 months after surgery | cystoid macular edema assessed by OCT (central subfield thickness \>310 micron, with presence of intraretinal cystic areas of low reflectivity in OPL) visual acuity |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| factors related to development of macular edema | from 1 month up to 6 months after surgery | demographics, systemic and ocular parameters |
Countries
Italy
Contacts
Primary ContactAntonio Longo, MD, PhD
Backup ContactMatteo R Fallico, MD, PhD
Outcome results
None listed