Acute Kidney Injury (AKI)
Conditions
Brief summary
The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals. Surgery-related AKI is a severe complication that is related not only to short-term complications as increases in mortality rate and development of cardiac complications but also with complications on long term, such as development of chronic kidney disease. A better understanding of the mechanism of this hypthesis will lead to better management of this complication.
Detailed description
A randomized blinded prospective study included 206patients who the candidate for major surgery at South Egypt Cancer Institute, Assiut University, Assiut, Egypt. From April 2018 till April 2019, a detailed history and careful examination, routine laboratory investigations were done, Baseline ECG was recorded 24hours before surgery and 48hours postoperative at ICU.
Interventions
DIAGNOSTIC_TESTKidney function test
Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours
Sponsors
South Egypt Cancer Institute
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* patients who were candidates for major non cardiac surgery
Exclusion criteria
* chronic cardiac diseases (myocardial ischemia, heart failure), Active severe infection, pregnancy, chronic kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Creatinine level | every 12 hours | Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours |
Countries
Egypt
Outcome results
None listed