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Post-COVID-19 Pneumo-hematocele

Post COVID-19 Pneumo-hematocele: Clinical Presentation and Treatment Pathway

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05067881
Acronym
PHC
Enrollment
37
Registered
2021-10-05
Start date
2020-03-01
Completion date
2021-09-20
Last updated
2021-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 Respiratory Infection

Keywords

COVID-19, Pneumohematocele, Giant bullae, Pneumatocele

Brief summary

Introduction. As the COVID-19 pandemic has continued, an increasing number of long-term complications are emerging. Recently, the appearance of characteristic pulmonary lesions has been noted, being described as post COVID-19 pneumatocele. The aim of this study is to describe the clinical, histopathologic and imaging features of post COVID-19 pneumo-hematoceles (PHC) and secondarily to suggest a treatment algorithm in these patients. Methods. A retrospective study was performed in patients admitted with diagnosis of SARS-CoV2 infection from March 2020 to September 2021 who presented PHC on imaging studies. Clinical and demographic variables were recorded and CT scans were analyzed. A logistic regression analysis was performed to determine the risk for rupture according to PHC characteristics. It appears that PHC occurs secondary to encapsulation of blood accumulation, the result of micro capillary bleeding, with partial reabsorption of blood and subsequent air filling. The recommendation is to operate on patients with PHC of 5cm and those with persistent lesions of 3cm.

Interventions

PROCEDUREPulmonary resection

Resection of pneumohematocele

Sponsors

Instituto Nacional de Enfermedades Respiratorias
CollaboratorOTHER_GOV
Hospital General Ajusco Medio
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Adults with a positive protein chain reaction for SARS-CoV2, * PHC on imaging studies.

Exclusion criteria

* loss of follow up * age out of range.

Design outcomes

Primary

MeasureTime frameDescription
PHC diagnosisFrom date of diagnosis until 4 weeks after diagnosisPneumohematoceles on imaging studies

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026