Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments

Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments: Impact of Risk Factors and Treatment Characteristics

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05065034

Acronym

PERIODONTITIS

Enrollment

200

Registered

2021-10-01

Start date

2021-09-29

Completion date

2023-06-25

Last updated

2021-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis, Adult

Keywords

Periodontitis, Inflammatory diseases, Periodontal, Teeth, Aesthetic morbidity, Cardiovascular risk, Supragingival, Subgingival, Biofilms, Prosthetic restorations

Brief summary

Antibiotics are currently used in periodontology to specifically target the most pathogenic bacteria in subgingival biofilms and to improve treatments. The multiplicity of protocols / dosages tested and the variability of the results did not make it possible to reach an international consensus on antibiotic therapy and its cost / benefit ratio, in particular with regard to the significant side effects of taking antibiotics (resistance bacterial). The care environment as well as the clinical, biological and microbiological parameters can strongly influence the results in usual treatment.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Patient over 18 years old * Patient treated for periodontitis between 01/01/2012 and 07/31/2021 * Patient whose medical and periodontal file contains all the elements necessary for data analysis * Subject not having expressed, after information, his opposition to the reuse of his medical data for the purposes of this research.

Exclusion criteria

* Patient who expressed his opposition to participating in the study * Patient without periodontitis * Patient smoking more than 10 cigarettes / day * Patient presenting a dilapidated oral state (untreated caries, unrestored teeth), oral infectious foci whose management requires antibiotic treatment during the initial treatment * Impossibility of giving the subject informed information * Subject under safeguard of justice * Subject under guardianship or guardianship

Design outcomes

Primary

Measure	Time frame
A retrospective study of the use of antibiotic therapy on the short and long-term results of periodontitis treatments	Files analysed retrospectively from January 01, 2012 to July 07, 2021 will be examined]

Countries

France

Contacts

Primary ContactJean-Luc DAVIDEAU, MD, PhD

jean.luc.davideau@chru-strasbourg.fr33 3 88 11 69 47

Backup ContactSaïd CHAYER, PhD, HDR

said.chayer@chru-strasbourg.fr

Outcome results