Right Ventricle, Thoracic Surgery
Conditions
Keywords
Right ventricle, speckle tracking, thoracic surgery
Brief summary
In postoperative thoracic surgery (lobe resection, pneumonectomy or wedge resection), cardiovascular complications are the most frequent (10 to 15%) with a significant morbi-mortality rate. Right ventricular (RV) dysfunction is a complication that can be multifactorial in post thoracic surgery. The RV longitudinal shortening fraction (RV-LSF) is a new 2D-STE parameters able to more accurately detect patients with RV dysfunction compared to conventional echocardiographic parameters. This project is a single-center, prospective, interventional study of patients hospitalized at the Amiens University Hospital for scheduled thoracic surgery. TTE is performed preoperatively, at day 2 and day 15 following the thoracic surgery. Echocardiographic parameters will be measured by an echocardiographic expert in offline with a dedicated software. MACE criteria will be collected at day 2, day 15 and day-30 following the thoracic surgery.
Interventions
the included patients have a TTE preoperatively in order to evaluate the RV systolic function. TTE will also be done at day 2 and day-15 during the follow-up surgical consultation.
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patient (\>18 years) * Patient hospitalized at the Amiens University Hospital for scheduled thoracic surgery (lobectomy, pneumonectomy, wedge resection). * Surgery by thoracotomy or video-assisted thoracic surgery * Information of the patient and collection of his non-opposition
Exclusion criteria
* Patient with poor echogenicity on TTE not allowing evaluation of 2D-STE or conventional parameters of the RV. * Patient with a rapid supraventricular rhythm disorder (HR \> 100) at the time of TTE * Patient under mechanical ventilation * Patient under extracorporeal membrane oxygenation * Patients under guardianship or legal protection * Patients whose clinical condition does not allow for their non-opposition * Pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| occurrence of a major cardiovascular event (MACE) | day 30 | MACE is a composite criteria. MACES criteria is defined as the occurrence of at least one of the following events: A cardiovascular death or a documented supraventricular tachycardia (atrial fibrillation and/or flutter) of duration \> 30 seconds or, an acute myocardial infarction or, an hospitalization for a right ventricular failure or, an hospitalization for a left ventricular failure. |
Secondary
| Measure | Time frame |
|---|---|
| Variation of RV systolic function from baseline in patients with MACE | at day 1 |
| Variation of RV systolic function from baseline in patients without MACE | at day 1 |
| Assessment of RV systolic function preoperatively | at day 30 |
| occurrence of a postoperative complication | at day 30 |
Countries
France
Contacts
Primary ContactChristophe Beyls, MD
Outcome results
None listed