Cerebral Palsy, Lower Urinary Tract Symptoms
Conditions
Keywords
cerebral palsy, lower urinary tract symptoms, Magnetic resonance imaging, brain lesion, incontinence
Brief summary
More than 50 % of children and adults with cerebral palsy experience lower urinary tract symptoms (LUTS). This can negatively influence quality of life of the child and the total social environment. Previous research demonstrated that the brain lesion, characteristic for cerebral palsy (CP), is a prognostic factor for the functional abilities of a child with CP. Previous research within our department demonstrated functional impairment as a risk factor for incontinence. This demonstrates an indirect connection between the brain lesion and incontinence of a child with CP. However, this connection isn't alway correct as some children with high functionality also demonstrate incontinence. As bladder control is also regulated by higher brain centers, the present study wants to investigate a direct connection between the brain lesion of the child, visible by means of MRI, and the incontinence status of the child. .
Detailed description
The current study is a cross-sectional observational study in which a correlation is investigated between known anatomical MRI results and the continence status of a child with CP. Although neuroimaging isn't seen as a requirement for the definition and diagnosis of CP2, MRI imaging is often part of diagnostic evaluation. The Surveillance of Cerebral Palsy in Europe (SCPE) working group composed the MRI classification system or MRICS classifying neuroimaging results in maldevelopments, predominant white matter injury, predominant grey matter injury, miscellaneous and normal. These results will be correlated with results of the validated Vancouver symptoms score for dysfunctional elimination syndrome.
Interventions
OTHERVancouver symptom score for dysfunctional elimination syndroms
Validated questionnaire concerning bladder and bowel symptoms
OTHERMagnetic resonance imaging
Known MRI results of the patient file
Sponsors
University Ghent
University Hospital, Ghent
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
5 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of cerebral palsy * MRI investigation in history * Dutch or French speaking child and parent
Exclusion criteria
* No MRI investigation in history * Child or parent not speaking Dutch or French
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incontinence ratio | During cross-sectional testing | Amount of patients with incontinence in the different MRICS-groups (MRI classification system for children with CP). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Amount of Lower urinary tract symptoms in different MRICS-groups | During cross-sectional testing | Score of 'Vancouver symptom score for dysfunctional elimination syndrome'-questionnaire and individual questions in the different MRICS- groups (MRI classification system for children with CP). |
| Amount of bladder symptoms in different MRICS-groups | During cross-sectional testing | Score of individual questions from the 'Vancouver symptom score for dysfunctional elimination syndrome' questionnaire in the different MRICS- groups (MRI classification system for children with CP). |
Countries
Belgium
Outcome results
None listed