Cancer
Conditions
Keywords
Low intensity Aerobic Exercise, ROM Exercise, Palliative Care
Brief summary
To compare the effect of low intensity aerobic exercise and active ROM exercises on cancer related fatigue and its associated symptoms and quality of life in cancer patients receiving palliative care.
Interventions
OTHERLow Intensity Aerobic Exercises Group
Intervention Low Intensity Aerobic Exercises i.e. stationary cycle(supervised) Intensity 55-65% of HRmax Frequency 3 times a week Duration 30 min each session
OTHERActive Exercises Group
Intervention Upper and lower limb ROM & stretching exercises Intensity As per tolerance Frequency 12 repetition/4sets per exercise 3 times/week Duration 30 minutes each session
Sponsors
Riphah International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* ability to give written consent. * Diagnosed advance cancer specifically gastrointestinal tract (GIT) cancer, Lung cancer and Breast cancer etc. (stage 2 and 3). * Intensity of fatigue ≥4 out of 10 on fatigue Numerical Rating Scale in first visit observation * Survival expectancy more than one month, * Functional status allowing the participants to participate in the proposed therapy.
Exclusion criteria
* Anemia (Hb ≤ 8g/dl), * Existence of other comorbidities causing fatigue (i.e. Parkinson's, Multiple sclerosis, Heart failure), * Infection requiring antibodies * bone metastases, * thrombocytopenia (\<50×109/l), * myocardial infarction within the past three months * uncontrolled hypertension (diastolic pressure \>95 mm Hg).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fatigue Numeric Rating Scale | 4th Week | The fatigue numeric rating scale (NRS) is a single-item measure assessing severity of fatigue. We will use this in our study to measure the severity of cancer related fatigue in oncology patients receiving palliative care. The fatigue NRS is a patient- administered, single- item, 11- point horizontal scale anchored at 0 and 10, with 0 representing 'no fatigue' and 10 representing 'as bad as participant can imagine'. Changes from the baseline to 4 week |
| Karnofsky Performance Status | 4 Week | The Karnofsky Performance Scale Index is an assessment tool for functional impairment. It can be used to compare effectiveness of different therapies and to assess the prognosis in individual patients. It is a standard way of measuring the ability of cancer patients to perform ordinary tasks. The Karnofsky Performance Status scores range from 0 to 100. A higher score means the patient is better able to carry out daily activities. Changes from the baseline to 4 week |
| Edmonton Symptom Assessment Scale (ESAS) | 4 week | This tool is designed to assess nine common symptoms experienced by cancer patients, including pain, tiredness, nausea, depression, anxiety, drowsiness, appetite, well-being, shortness of breath. The severity for each symptom ranges from 0 to 10 where 0 means absence of symptom to 10 being the worst possible severity. Changes from the baseline to 4 week |
| Brief Fatigue Inventory (BFI): | 4 week | It is used to rapidly assess the severity and impact of cancer-related fatigue on daily functioning in past 24 hours, which requires a very short time to fill and the global fatigue scoring can be obtained by averaging all the 4 items on the BFI. Changes from the baseline to 4 week |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life questionnaire for cancer patients treated with anti-cancer drugs (QOL-ACD): | 4 week | Quality of Life Anti-Cancer Drugs (QOL-ACD) is a Quality-of-life measurement tool for patients undergoing chemotherapy it has 22 items, divided into these categories: daily activities, physical condition, social activities, mental and psychological status. Scaling of items is from 5 to 1(5 being worst and 1 being good) for 21 items, and a five-point face scale for 1 item. Changes from the baseline to 4 week |
Countries
Pakistan
Outcome results
None listed