Heart Failure With Preserved Ejection Fraction
Conditions
Brief summary
Heart failure with preserved ejection fraction (HFpEF) was considered as a heterogeneous disease with multi-organ and multi-system design, which is related to various complications, such as hypertension, obesity and arteriosclerosis. Ambulatory arterial stiffness index (AASI) is associated with arteriosclerosis and hypertension. There is no report on whether AASI is associated with left ventricular diastolic dysfunction in patients with HFpEF.
Detailed description
Heart failure with preserved ejection fraction (HFpEF) is related to various complications, such as hypertension, obesity and arteriosclerosis. Ambulatory arterial stiffness index (AASI) is associated with arteriosclerosis and hypertension. AASI is especially associated with left ventricular diastolic dysfunction in patients with hypertension. Patients with HFpEF have obvious left ventricular diastolic insufficiency. However, there is still no research investigating the the relationship between AASI and left ventricular diastolic dysfunction in patients with HFpEF.
Interventions
None listed
Sponsors
Dongying Zhang
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adult aged \>=18years old; Diagnosed with HFpEF.
Exclusion criteria
LVEF less than 45% at any time; Severe liver failure; Other causes of shortness of breath, such as severe pulmonary disease or severe Severe valvular disease of the left heart; Chronically bedridden or incapacitated; Age \<18 years old.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Left ventricular diastolic function | 1 day On admission | the ratio of mitral peak velocity of early filling to early diastolic mitral annular velocity(E/e') |
Countries
China
Contacts
Primary ContactZhang Dongying
Outcome results
None listed