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Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.

Effects of Blood Flow Restriction Training vs Traditional Exercise in Patients With Knee Osteoarthritis.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05058794
Enrollment
42
Registered
2021-09-28
Start date
2021-10-10
Completion date
2022-02-11
Last updated
2022-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophy, Osteoarthritis, Knee

Keywords

Osteoarthritis, Blood Flow Restriction, Quadriceps, Resistance Training

Brief summary

The main objective of the study is to compare the effects of Blood flow Restriction training vs. traditional exercises on knee pain , knee functional disability and on quadriceps strength in patient with knee osteoarthritis.

Detailed description

Osteoarthritis is a degenerative disease affecting the most commonly weight bearing joint.The common form of arthritis is osteoarthritis (OA) causing structural changes in the joint. Age is a common factor affecting the strength and muscle mass.Worldwide there is a drastic increase of osteoarthritis in the older population. In the past 20 years the prevalence of knee pain increased and reached up to 50% in the older population. The most common OA affecting lower extremity is in the knee Joint.Majority of the people affected by knee OA are the older population. Knee Joints being the most weight bearing joint affected in OA causing pain , limiting function and mobility.Mobility and function may be affected in osteoarthritic population usually experience pain and stiffness. The main objective of this study is to compare the Effects of blood Flow restriction training vs conventional treatment exercises on knee pain, functional disability and quadriceps strengthening. The main purpose of this study is to improve the muscular strength of lower limbs which are being affected in a disease osteoarthritis in the adult population.

Interventions

OTHERBlood flow Restriction/Resistance Training

During each exercise, only blood flow in the involved leg was restricted using an aneroid sphygmomanometer. Prior to exercise the cuff was placed on the most proximal portion of the limb and limb occlusion pressure (LOP) was calculated in the body position that the Blood flow Restriction (BFR) stimulus would be applied. Blood Flow Restriction BFR pressure was set at 50% occlusion. Resistance applied for 1 minute (60 sec) with 30 % load of 1 repetition maximum. Subjects will receive treatment bilaterally. Participants will perform exercises 2 sets with 15 repetitions through 0 to 90 degrees.

OTHERConventional Therapy Group

Resistance applied for 1 minute (60 sec) with 30 % load of 1 repetition maximum. Subjects will receive treatment bilaterally.participants will perform 2 sets with 15 repetitions in (0 to 90 degree.)

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Pain : Subjects having unilateral or bilateral pain * Pain type : subjects having chronic pain * Includes diagnosed cases of knee osteoarthritis * grades 2-3 according to the Kellgren and Lawrence method of grading * Includes knee osteoarthritis patients with lateral tracking of patella which will assessed through Q angle test

Exclusion criteria

* Any other orthopaedic or neurological condition of hip and knee * Sign and symptoms of lower motor neuron disease * Current use of medication * Radiculopathy * Fracture * Malignancy * Thromboembolism * Decreased range of motion

Design outcomes

Primary

MeasureTime frameDescription
Muscle strength6 weeksMeasurement of Quadriceps strength with portable weight machine.
Thigh Girth6 weeksParticipants will be supine lying and knee in extension, standing or knee at 90 degree. Proximal to the patellar pole superiorly one measurement with a non-elastic tape at the inguinal fold, then mark the mid-point at the mid-thigh level measuring in centimeters/inches.
Numeric Pain Rating Scale ( NPRS)6 weeksPatient will be asked if there is any pain in knee from the scale of 0 to 10.
Q angle Measurement6 weeksSubject will be in supine position with knee extension and quadriceps are relaxed, examiner will measure the q angle with flexible inch tape and goniometer. The Q- angle is measured by extending a line through the center of the patella to the anterior superior iliac spine and another line from the tibial tubercle through the center of the patella.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026