Prospective Registry for Patients With Chest Pain in Emergency Department

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05058300

Acronym

ThReg

Enrollment

3000

Registered

2021-09-27

Start date

2017-09-20

Completion date

2024-10-11

Last updated

2023-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chest Pain

Keywords

Chest Pain

Brief summary

monocentric, prospective registry collection of clinical data of all patients with chest pain in emergency department and follow-up after 30 days

Detailed description

An unselected patient-population with chest pain entering through the emergency department participate in a diagnostic survey where a chest pain algorithm based mainly on risk scores (Grace, TIMI, Heart) verifying the diagnostic forecasting power (sensitivity, specificity, negative and positive predictive value) of biomarkers, risk scores and imaging methods for diagnosing of potential life-threatening disease.

Interventions

DEVICECT Thorax

CT Thorax (GE Revolution with chest pain algorithm)

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \>18 years old chest pain written confirmation of participants or legal representative

Exclusion criteria

* thorax trauma

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic forecast of biomarkers, risk scores and computer tomography	From admission to emergency unit discharge	Diagnostic forecast compared to the initial suspected diagnosis and discharge diagnosis

Secondary

Measure	Time frame	Description
Sensitivity	During diagnostic procedure	Sensitivity in result of biomarkers, risk scores and imaging methods
Specificity	During diagnostic procedure	Specificity in result of biomarkers, risk scores and imaging methods
Positive predictive value	During diagnostic procedure	Positive predictive value in result of biomarkers, risk scores and imaging methods
Negative predictive value	During diagnostic procedure	Negative predictive value in result of biomarkers, risk scores and imaging methods
Major adverse cardiac events (MACE)	From admission to emergency unit until 30 days after or death	outcome is measured by coronary intervention, coronary bypass and death within 30 days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026