Fetal Anomaly of Central Nervous System
Conditions
Keywords
Sonography ,neurlogical anomalies
Brief summary
This is a descriptive cross-sectional study 300 patients coming for antenatal care at sohag governorate undergo mid anatomical scan. Samples 300 pregnant women have mid anatomical scan at 20-22 weeks as routine antenatal care and Examination of the fetal CNS will be performed with a high resolution two dimensional ultrasound machine (Voluson E8) equipped with a RAB 4 to 8MHz multifrequency transabdominal Probe. Four standard recommended views-transventricular, falx, cavum, and posterior fossa or transcerebellar views-provide an overview of fetal intracranial anatomy during the second trimester anatomy scan. Follow-up information will be obtained in all cases, and all infants will be considered healthy by pediatric examination. In selected cases, postnatal single-shot fast spin-echo magnetic resonance (MR) imaging will be performed as integrated, complementary investigation.to confirm diagnosis.
Detailed description
1. Type of the study: This is a descriptive cross-sectional study 2. Study Setting: 300 patients coming for antenatal care at sohag governorate undergo routine second trimester scan. 3. patients and methods: Inclusion criteria: 1. All pregnant females of 18 to 45 years old. 2. gestational age of 20- 22 gestational week . Exclusion criteria: 1-age less than18years and more than 45 years. gestational age less or more than20- 22 weeks. Samples Methods 300 pregnant women low risk pregnancy will be scanned at 20-22 weeks as routine antenatal care and Examination of the fetal CNS will be performed with a high resolution two dimintional ultrasound machine (Voluson E8) equipped with a RAB 4 to 8MHz multifrequency transabdominal Probe. Four standard recommended views-transventricular, falx, cavum, and posterior fossa or transcerebellar views-provide an overview of fetal intracranial anatomy during the second trimester anatomy scan. Follow-up information will be obtained in all cases, and all infants will be considered healthy by pediatric examination. In selected cases, postnatal single-shot fast spin-echo magnetic resonance (MR) imaging will be performed as integrated, complementary investigation.to confirm diagnosis.
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
CASE_CROSSOVER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* All pregnant females of 18 to 45 years old. * gestatioal age of 20- 22 gestational week .
Exclusion criteria
* age less than18years and more than 45 years. * gestational age less or more than20- 22 weeks.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of sonography in the diagnosis of neurological fetal anomalies | From 20 _ 22 gestational age ...confirmation occursat birth till 1 week post natal | Investigator compares the accuracy of songraphy in the diagnosis of neurological fetal anomalies with post natal diagnosis by either clinically or by MRIThis is a descriptive cross-sectional study 2- Study Setting: 300 patients coming for antenatal care at sohag governorate undergo mid anatomical scanExamination of the fetal CNS will be performed with a high resolution two dimintional ultrasound machine (Voluson E8) equipped with a RAB 4 to 8MHz multifrequency transabdominal Probe. Four standard recommended views-transventricular, falx, cavum, and posterior fossa or transcerebellar views-provide an overview of fetal intracranial anatomy during the second trimester anatomy scan. After birth ,investigator reports anomalies clinically or after consultation of pediatric department. |
Countries
Egypt
Contacts
Primary ContactBothyna Za Elsayed, Assistant. lecturer
Outcome results
None listed