Evaluation of Respiratory Muscle in Patient With Pulmonary Arterial Hypertension

Evaluation of Primary and Accessory Respiratory Muscles and Their Influence on Exercise Capacity and Dyspnea in Pulmonary Arterial Hypertension

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05056532

Enrollment

Registered

2021-09-24

Start date

2021-09-09

Completion date

2022-04-18

Last updated

2022-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Artery Hypertension

Keywords

respiratory muscle strength, exercise capacity, dyspnea, accessory respiratory muscle

Brief summary

The aim of the study is that evaluation of basic and accessory respiratory muscles and their relationship of six minute walk test in patient with pulmonary arterial hypertension (PAH)

Interventions

DIAGNOSTIC_TESTpatient assessment

subjective and objective measurement will be performed in patients with PAH

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 64 Years

Healthy volunteers

Yes

Inclusion criteria

* patients with diagnosis of pulmonary arterial hypertension * patients with stabil drug therapy at least three months

Exclusion criteria

* patients with obstructive and/ or restrictive lung disease comorbidity * severe orthopedic and/ or neurological comorbidity * patients with heart failure * patients with ischemic heart disease * uncooperative patients

Design outcomes

Primary

Measure	Time frame	Description
pectoralis muscle strength	15 minute	pectoralis muscle strength will be evaluated with hand held dynamometers according to muscle test technique
serratus anterior muscle strength	15 minutes	Serratus anterior muscle strength will be evaluated with hand held dynamometers according to muscle test technique
sternocleidomasteoideus muscle strength	15 minutes	sternocleidomasteoideus muscle strength will be evaluated with hand held dynamometers according to muscle test technique
Respiratory mouth pressure	15 minutes	Respiratory mouth pressure will be measured to determine maximally inspiratory pressure and maximally expiratory pressure according to ATS/ERS guidelines.

Secondary

Measure	Time frame	Description
Six Minute Walk Test (6MWT)	30 minutes	Six minute walk test will be performed to evalute functionally exercise capacity according to ATS/ERS guidelines
Dyspnea assessment	20 minutes	London Chest Activity of Daily Living Scale will be used to sensation of dyspnea during activity of daily living.The scale consists of four domains: self-care (four items), domestic (six items), physical (two items) and leisure (three items). In total, the scale consisting of 15 items scored of 0 to 5. 0 means that I wouldn't do anyway and 5 means that Someone else does it for me. Higher values indicate greater limitation due to the dyspnea

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026