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Early Cardiac Extubation After Cardiac Surgery

Early Cardiac Extubation After Cardiac Surgery: a Retrospective Single-center Non-inferiority Trial

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05050435
Enrollment
500
Registered
2021-09-20
Start date
2021-08-30
Completion date
2021-12-31
Last updated
2021-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Cardiac Surgery

Keywords

post-operative complications, on table extubation

Brief summary

The management of heart valve disease is constantly evolving over time. The minimally invasive approach (mini-thoracotomy and J-hemisternotomy) is one of the major surgical evolutions. It has many advantages including, among others, a reduction of postoperative pain and the preservation of sternal stability This evolution of the surgical technique towards a less invasive approach encouraged the investigators to adapt the anesthetic management accordingly. In particular, immediate postoperative extubation appeared feasible. The investigators would therefore like to test the hypothesis that immediate extuation is non-inferior to delayed extubation with regard to patient safety. The investigators also investigated whether immediate extubation could be beneficiel in terms of vasopressors requirement, risk of early postoperative complications, fluid balance and length of stay in the intesive care unit and in the hopsital.

Interventions

Patients of the 2 groups are extubated at different moments: either immediately postoperatively, in the operating room, or after a few hours monitoring in ICU

Sponsors

University of Liege
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Minimally invasive valve replacement intervention (thoracotomy or J-hemisternotomy)

Exclusion criteria

* Combined surgery

Design outcomes

Primary

MeasureTime frameDescription
Post-operative complications30 daysIntensive care unit length of stay (days)

Countries

Belgium

Contacts

Primary ContactOceane Jaquet
jaquet.oceane@gmail.com0032479760411

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026