Echocardiographic Findings in Infants of Diabetic Mothers and Its Relation to Maternal Glycemic Control

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05050058

Enrollment

Registered

2021-09-20

Start date

2020-03-08

Completion date

2021-06-20

Last updated

2022-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant of Diabetic Mother

Brief summary

The aim of this work was to: 1. Evaluate the use of echocardiography in the assessment of hemodynamic stability in newborns. 2. Determine the prevalence of congenital heart diseases or any cardiac abnormalities in infants born to diabetic mother in relation to the glycemic control of their mothers

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

0 Days to 7 Days

Healthy volunteers

Inclusion criteria

* Infant of diabetic mother (IDM) (pregestational and gestational diabetes) born in Alexandria University Children 's Hospital (AUCH) whatever their weight or their gestational age

Exclusion criteria

* Neonates aged more 7 days. * Patient born outside the tertiary center of Alexandria University Children 's Hospital.

Design outcomes

Primary

Measure	Time frame	Description
Detection of incidence of congenital heart disease in infants of diabetic mothers	First week	This was done using echocardiography: two-dimensional study, color Doppler, pulsed and continuous wave Doppler as well as m-mode study.
Hemodynamic significance of patent ductus arteriosus (PDA)and patent Foramen Ovale (PFO)	First two months of life	This was done using echocardiography: two-dimensional study, color Doppler, pulsed and continuous wave Doppler as well as m-mode study for assessments of PDA and PFO in infants of diabetic mothers in comparison with healthy controls.
Assessment of left ventricular dimensions in infants of diabetic mothers in comparison to healthy controls.	First two months of life	Using M-mode images under guidance of two dimensional echocardiography in parasternal long axis view was done for all participants measuring of the following: * Left ventricular end systolic diameter (LVDs). * Left ventricular end diastolic diameter (LVDd). * Inter ventricular septal diameter (IVSd). * Left ventricular posterior wall thickness during diastole (LVPWd). * Left ventricular posterior wall thickness during systole (LVPWs) those measures are compared in infant of diabetic mothers and healthy controls.

Countries

Egypt

Outcome results