Pregnancy Loss, Early
Conditions
Brief summary
The clinical practice recommendations highlight the fact that the patient's choice concerning the management of her aborted pregnancy in the first trimester should be privileged, after clear and appropriate information on the available treatments, in order to improve his experience and reduce the negative psychological symptoms that can generate an alteration in the quality of life, in the aftermath of the loss of pregnancy. The present study will describe the efficacy, satisfaction and tolerance of patients benefiting from medical treatment with Mifégyne® and MisoOne® versus those benefiting from surgical treatment by endo-uterine aspiration for the management of a pregnancy stopped during the first trimester at the Toulouse University Hospital
Interventions
DRUGMedical treatment with Mifégyne® and MisoOne®
When participants arrive for their uterine emptiness check-up, 12 days after treatment, patients will be asked to drop off the study questionnaire the same day in a box provided for this purpose in the department.
PROCEDUREEndo-uterine aspiration
When patients arrive in hospital on the day of the surgery, participants will be asked to complete a questionnaire at home 1 week after surgery and return it to investigators.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Any adult patient presenting to the gynecological emergency department of the Paule de Viguier Hospital in Toulouse for whom a diagnosis of an arrested pregnancy in the first trimester is made * Whose cranio-caudal length of the embryo measured by ultrasound is less than 25 mm or having a clear egg * Having agreed to the study (written or verbal) after clear and fair information * Who understands and reads French
Exclusion criteria
* Medical contraindication to treatment with Mifégyne® or MisoOne® * Hemodynamically unstable patient requiring urgent surgical treatment. * Protected adult patient (guardianship, curatorship, safeguard of justice)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with treatment-related adverse events as assessed by CTCAE v4.0 | Inclusion day (day 0) | — |
| Patient satisfaction | Inclusion day (day 0) | Completing the satisfaction questionnaire |
Countries
France
Outcome results
None listed