Obstructive Sleep Apnea, Sleep Apnea Syndromes, Tonsillar Hypertrophy
Conditions
Keywords
tonsillectomy, obstructive sleep apnea, tonsil surgery
Brief summary
Long-term results of tonsillectomy in the treatment of obstructive sleep apnea in adults
Detailed description
The investigators are studying long-term efficiency of tonsillectomy in adults with obstructive sleep apnea caused by tonsillar hypertrophy. These patients have undergone tonsillectomy in 2004-2018 and now 3-17 years later investigators will perform new polysomnographies and compare these results with preoperative values. Especially the reduction in apnea-hypopnea index (AHI) will be evaluated. The quality of life and possible symptoms will be measured with questionnaires.
Interventions
DEVICEPolysomnography
Polysomnography is performed one time overnight
Sponsors
Turku University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age at least 16 during tonsillectomy * preoperative obstructive sleep apnea and AHI (apnea-hypopnea index) \> 14 * tonsillectomy has been done because of the symptoms caused by tonsillar hypertrophy (ICD-10 diagnostic codes G47.3, R06.5 or J35.1) * in addition to tonsillectomy, patients may have undergone shortening of uvula and/or radio frequency ablation of soft palate
Exclusion criteria
* AHI \< 14 * in addition to tonsillectomy patient has undergone uvulectomy, uvulopalatoplasty, uvulopalatopharyngoplasty or mandibular advancement * other, evaluated by investigator
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Apnea-hypopnea index | 3-17 years | Post-operative apnea-hypopnea index (AHI) reduction by 50% compared to preoperative values in polysomnography. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life measured by Glasgow Benefit Inventory (GBI) | 3-17 years | General quality of life questionnaire. 18 questions, score 1-5 in each question, higher is better. |
| Quality of life measured by Epworth sleepiness scale (ESS) | 3-17 years | Questions regarding sleepiness. Score 0-24, lower is better. |
| Apnea-index (AI) | 3-17 years | Post-operative apnea index reduction compared to preoperative values in polysomnography. |
| Snoring time | 3-17 years | Post-operative reduction of snoring time compared to preoperative values in polysomnography |
| Oxygen Desaturation Index (ODI) | 3-17 years | Post-operative reduction of oxygen desaturation index compared to preoperative values in polysomnography |
Countries
Finland
Outcome results
None listed