Breast Cancer
Conditions
Brief summary
Breast cancer is the most frequently observed cancer in women in France.The mortality rate is still decreasing with a decrease of 1.6% per year between 2010 and 2018, explained by the improvement in available treatments.For patients with breast cancer expressing hormone receptors, treatment with Tamoxifen or anti-aromatase can have the risk of the cancer coming back.However, these treatments have many side effects, including the risk of osteoporosis and metabolic disorders with anti-aromatases; and arterial and thromboembolic accidents with Tamoxifen.These effects have been well studied while taking hormone therapy.However, very few studies have analyzed the impact of these treatments after stopping them in women who have had non-metastatic hormone-sensitive breast cancer and uncertainties persist on the evolution of the health risk after initial treatment.
Interventions
OTHERQuestionnaire
A questionnaire will be given to patients who will ask them about their possible fractures, their bone and oncological follow-ups and their possible cardiovascular events since the end of treatment with hormone therapy.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients who had T1-T3, N0-N2, M0 breast cancer * Patients referred to the Menopause center in the context of their breast cancer who were included in the original study evaluating the bone impact of hormone therapy carried out between 2010 Bone and cardiovascular impact of adjuvant hormone therapy for cancer non-metastatic breast * Patient who has given her consent for the study (written or verbal) after clear and fair information
Exclusion criteria
* Metastatic breast tumor * Absence of adjuvant hormone therapy for patients whose tumor did not express hormone receptors * Patients who have died since the last assessment * Protected adult patient (guardianship, curatorship, safeguard of justice)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate the bone impact of hormone therapy remotely | Inclusion day (day 0) | A questionnaire asking patients if they have fractures since stopping the treatment will be offered. |
| Evaluate the cardiovascular impact of hormone therapy remotely | Inclusion day (day 0) | A questionnaire asking patients if they have had a cardiovascular problem since stopping treatment will be offered. |
Countries
France
Outcome results
None listed