Arrhythmias, Cardiac, Cardiovascular Diseases, COVID-19 Acute Respiratory Distress Syndrome
Conditions
Keywords
COVID-19, electrocardiogram, ARDS, Prone position
Brief summary
Prolonged prone position ventilation reduces the 30-day mortality in acute respiratory distress syndrome (ARDS) and in COVID-19 infection. A large number of patients with COVID-19 suffered from new-onset cardiac disease, therefore, ECG is crucial. However, there is limited data on the effects of prone position on the ECG in COVID-19 patients.
Detailed description
Prolonged prone position ventilation reduces the 30-day mortality in acute respiratory distress syndrome (ARDS) and in COVID-19 infection. The evidence showed that a large number of patients with COVID-19 suffered from new-onset cardiac disease due to inflammatory processes or cytokine storm, therefore, ECG is crucial for making the diagnosis including arrhythmias and myocardial infarction. However, there is limited data on the effects of prone position on the ECG in COVID-19 patients. Therefore, we aimed to identify differences of electrical parameters between prone position and standard ECG including the difference in amplitude and duration of P, QRS, PR interval, QT interval, ST-segment between both positions (supine and prone). Furthermore, we aimed to compare clinical diagnosis from EKG between prone position and standard ECG by the cardiologists.
Interventions
DIAGNOSTIC_TESTelectrocardiogram
Prone position electrocardiogram
Sponsors
Khon Kaen University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* COVID-19 patients who were admitted to the COVID-19 specialized ward * Age 18 -80 years old * Suffered from pulmonary infiltration
Exclusion criteria
* Intubated patients * Cardiac arrest patients whether at presentation or during the study period * ECG cannot be performed due to anatomical defects or superficial skin problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of P wave amplitude | The first day of admission | The relative changes in P-wave amplitudes with different body positions were evaluated by dividing the 12-lead ECG into subregions (I, aVL: lateral limb leads; II, III, and aVF: inferior leads; V1 to V3: anterior precordial leads; V4 to V6: lateral precordial leads). |
| The change of QRS-complex amplitude | The first day of admission | The relative changes in QRS-complex amplitudes with different body positions were evaluated by dividing the 12-lead ECG into subregions (I, aVL: lateral limb leads; II, III, and aVF: inferior leads; V1 to V3: anterior precordial leads; V4 to V6: lateral precordial leads). |
| The change of T wave amplitude | The first day of admission | The relative changes in T wave amplitudes with different body positions were evaluated by dividing the 12-lead ECG into subregions (I, aVL: lateral limb leads; II, III, and aVF: inferior leads; V1 to V3: anterior precordial leads; V4 to V6: lateral precordial leads). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diagnosis | The first day of admission. | The EKG diagnosis from prone position and standard supine position which perform in the same time, in the same patient, by a cardiologist will be compared. |
Countries
Thailand
Contacts
Primary ContactPraew Kotruchin, MD, PhD.
Outcome results
None listed