Pain, Propofol Adverse Reaction, Transcutaneous Electrical Nerve Stimulation
Conditions
Brief summary
Propofol, an intravenous sedative agent, frequently produces pain during injection. This study was designed to investigate whether transcutaneous electrical nerve stimulation could reduce pain during propofol injection. in minimizing propofol injection pain.
Detailed description
Twenty min after transcutaneous electrical nerve stimulation, the electrodes were removed and propofol 0.5 mg/kg was administered at the rate of 0.5 ml/sec using syringe pump. Propofol injection pain was evaluated by a study blinded anesthesiologist using a four point scale: 0=no (negative response to questioning), 1=mild pain (pain reported only in response to questioning without any behavioral sings), 2=moderate pain (pain reported in response to questioning and accompanied by a behavioral signs or pain reported spontaneously without questioning, 3=severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal or tears).
Interventions
DEVICEtranscutaneous electrical nerve stimulation
transcutaneous electrical nerve stimulation group received transcutaneous electrical nerve stimulation via two electrodes on the venous cannulation site 20 min before propofol injection
Placebo transcutaneous electrical nerve stimulation group received no transcutaneous electrical nerve stimulation via two electrodes on the venous cannulation site 20 min before propofol injection
Sponsors
Kyungpook National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Masking description
Two electrodes were attached to the radial side of dominant forearm. In the placebo group the TENS device had no current output although the power on indicator light remained active.
Intervention model description
TENS YW-5000 (YoungWon Medical Co, Korea)
Eligibility
Sex/Gender
ALL
Age
19 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
\-
Exclusion criteria
* American Society of Anesthesiologists physical status classification \> 3 * Patient with a history of allergy to drugs * Patient who takes opioid, sedative, anticonvulsant * Patient with a history of neurologic disease and psychological disorders * patient with skin problem * Patient with pacemaker or electric medical device * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain during propofol injection | 15 seconds | Propofol injection pain was evaluated by a study blinded anesthesiologist using a four point scale |
Countries
South Korea
Contacts
Primary ContactYounghoon Jeon, Dr
Backup ContactYounghoon Jeon
Outcome results
None listed