Gingival Recession
Conditions
Keywords
connective tissue graft, tunneling flap procedure, hyaluronic acid
Brief summary
Microsurgical tunneling flap procedures using connective tissue grafts (CTG) are predictable for treating teeth with gingival recessions. Cross-linked hyaluronic acid can be used in conjunction with subepithelial palatal connective tissue grafts to improve postsurgical results. The aim of this study is to evaluate clinically the use of tunnel technique with CTG and cross-linked hyaluronic acid in addition to CTG alone for the treatment of multiple gingival recessions.
Detailed description
The treatment of multiple adjacent recession appears to be challenging for the clinician due to large surgical field, variation in teeth position in the dental arch (prominent roots), variation in recession size, thin phenotype and insufficient keratinized tissue in many teeth. Surgical treatment of all multiple recession in one dental arch during one session appears to be optimum. Surgical treatment time is longer, however patient doesn't need to undergo multiple surgeries, pharmacological therapies and postsurgical instructions. Esthetic concern seems to be one of the most common complaints from patients. Among utilized surgical techniques tunneling flap procedures using connective tissue grafts (CTG) with or without biologics such as an enamel matrix derivative (EMD) or hyaluronic acid (HA) provided the most successful outcomes for the treatment. Cross-linked hyaluronic acid can be used in conjunction with subepithelial palatal connective tissue grafts to improve postsurgical results and improving healing process. The aim of this study is to evaluate clinically the use of tunnel technique with CTG and cross-linked hyaluronic acid in addition to CTG alone for the treatment of multiple gingival recessions.
Interventions
DEVICEThe tunnel technique for root coverage with CTG without Cross-linked Hyaluronic Acid
The tunnel technique for root coverage with CTG without Cross-linked Hyaluronic Acid
DEVICEThe tunnel technique for root coverage with CTG andCross-linked Hyaluronic Acid
The tunnel technique for root coverage with CTG andCross-linked Hyaluronic Acid
Sponsors
Medical University of Warsaw
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years * Bilateral multiple gingival recessions in homologous teeth
Exclusion criteria
* Full-mouth plaque index ≥ 20% (Ainamo & Bay 1975) * Full-mouth sulcus bleeding index ≥ 15% (Mühlemann & Son 1971) * Smoking * Systemic diseases with compromised healing potential of infectious diseases * Drugs affecting periodontal health / healing * Pregnant and lactating females * Previous periodontal surgery in the area
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal parameters measured before surgery. | 1-7 days before surgery | 1. Probing pocket depth (PPD) MEASURED IN MILIMETERS: distance from the gingival margin to the bottom of the gingival sulcus 2. Clinical attachment level (CAL) MEASURED IN MILIMETERS: distance from the cementoenamel junction to the bottom of the gingival sulcus 3. Recession height (RH) MEASURED IN MILIMETERS: distance from the cementoenamel junction to the gingival margin 4. Width of keratinized tissue (WKT) MEASURED IN MILIMETERS: distance between the most apical point of the gingival margin and the mucogingival junction 5. Gingival thickness (GT) MEASURED IN MILIMETERS: thickness of the gingiva measured 2-3 mm apical to the gingival margin |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal parameters measured after surgery. | 12 months after surgery | 1. Probing pocket depth (PPD): distance from the gingival margin to the bottom of the gingival sulcus 2. Clinical attachment level (CAL): distance from the cementoenamel junction to the bottom of the gingival sulcus 3. Recession height (RH): distance from the cementoenamel junction to the gingival margin 4. Width of keratinized tissue (WKT): distance between the most apical point of the gingival margin and the mucogingival junction 5. Gingival thickness (GT): thickness of the gingiva measured 2-3 mm apical to the gingival margin ALL ABOVE PARAMETERS ARE MEASURED IN MILIMETERS |
Other
| Measure | Time frame | Description |
|---|---|---|
| Patient-reported outcomes based on VAS scales | 2 weeks after surgery | Questionnaires: Scale 1: Pain after surgery (during recent 2 weeks) from 0 (no pain) to 10 (very big pain) |
Countries
Poland
Contacts
Primary ContactBeata Wyrębek, PhD
Backup ContactBartłomiej Górski, PhD
Outcome results
None listed