Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05044689

Enrollment

800

Registered

2021-09-16

Start date

2021-04-12

Completion date

2026-12-31

Last updated

2025-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Colorectal Cancer

Brief summary

This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria. Both cases and controls will be required to complete a risk factor questionnaire which contains information about their diet, physical activity, past medical history and life style factors. They will also be required to provide information on their body composition through the use of a bioimpedance machine which measures the body mass index, fat and total body water percentage. Based on the existing ARGO platform where a current colorectal cancer study is going on, approximately 400 patients with a prior diagnosis or a new diagnosis will be recruited into this study. Comparatively, we will select our 400 controls from two groups of participants who are free of cancer and gastrointestinal diseases.

Interventions

BEHAVIORALQuestionnaire

Questionnaire containing questions regarding diet, physical activity, past medical history and life style practices.

DEVICEBioimpedance/Body Composition Unit

Patients will provide information on body composition through the use of a bioimpedance machine which measures the body mass index, fat and total body water.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

Case Group - Patients must have histologically confirmed diagnosis of colorectal or breast cancer. Control Group - Patients must not have a diagnosis of cancer.

Design outcomes

Primary

Measure	Time frame	Description
Development and Validation of Questionnaire For Assessing Modifiable Risk Factors for Cancer in Sub-Saharan Africa	2 years	—
Determination of Novel Modifiable Cancer Risk Factors in a Nigerian Population	2 years	We will determine the presence of established, plausible, and novel cancer risk factors in cases (n=400) and controls (n=400) in Nigeria

Countries

Nigeria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026