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Does Inclusion of Viral Prescription Pad Resources Increase Responsiveness to Feedback About Antibiotic Prescribing in Primary Care

Do Peer-comparisons, Emphasis on Harms, and/or Inclusion of Viral Prescription Pad Resources Increase Responsiveness to Feedback About Antibiotic Prescribing in Primary Care: Protocol for Two Linked Trials With Embedded Process Evaluations (OH Trial)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05044052
Enrollment
3379
Registered
2021-09-14
Start date
2021-12-15
Completion date
2022-12-15
Last updated
2023-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection

Keywords

audit and feedback, antibiotics

Brief summary

Antibiotic overuse is common and antibiotic prescribing contributes to rising rates of antimicrobial resistance. Primary care physicians prescribe the majority of all antibiotics and there is large inter-physician variability in prescribing that cannot be explained by differences in patient populations. In Ontario, audit and feedback (A&F) is routinely offered to primary care providers from a variety of sources. Ontario Health - an agency created by the Government of Ontario - provides A&F via email to physicians who voluntarily sign up for their MyPractice reports. These are multi-topic reports with aggregated (physician-level) data. As of November 2021, the MyPractice reports for family physicians will include data on antibiotic prescribing. To date, less than half of Ontario family physicians have signed up for the MyPractice reports from Ontario Health. For this study, the investigators will conduct a trial to investigate the effect of adding viral prescription pad resources to family physician A&F received through a MyPractice: Primary Care report. This evaluation provides an opportunity to determine if the addition of this resource to an A&F intervention increases changes to antibiotic prescribing.

Detailed description

This study will examine ways to optimize the effects of A&F for antibiotic prescribing in primary care. This study will aim to determine if emphasis (or not) on the use of a viral prescription pad developed by Choosing Wisely Canada (CWC) can help physicians act upon the feedback from their MyPractice report to reduce their antibiotic prescribing. Antibiotic prescribing feedback within the multi-topic MyPractice: Primary Care report will be sent to family physicians who signed up for this program from Ontario Health. This report includes a link to the Choosing Wisely viral prescription pad. Physicians will be randomized to the control group or intervention group. Physicians in the intervention group will receive additional emphasis on the use of the viral prescription pad and will also have a paper copy of the prescription pad mailed to their practice. One month after the initial intervention, participants will be invited to complete a process evaluation survey to determine why or why not the intervention worked and how individual factors can affect physician motivation, willingness, and ability to engage in new practices. Intervention participants will also be invited to take part in a process evaluation interview.

Interventions

BEHAVIORALEmphasis on the Choosing Wisely Viral Prescription Pad

We will investigate the effects of emphasizing the use of materials developed by Choosing Wisely Canada (CWC) - namely the viral prescription pad - to help physicians act upon the feedback to reduce their prescribing.

Sponsors

Ontario Agency for Health Protection and Promotion
CollaboratorOTHER_GOV
College of Family Physicians of Canada
CollaboratorOTHER
Canadian Institutes of Health Research (CIHR)
CollaboratorOTHER_GOV
Women's College Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Investigator, Outcomes Assessor)

Intervention model description

Cluster Randomized Control Trial

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Family physicians who sign up for the MyPractice reports by September 2021

Exclusion criteria

* Family physicians who did not sign up for the MyPractice reports by September 2021

Design outcomes

Primary

MeasureTime frameDescription
Antibiotic prescribing rate6 monthsTotal number of antibiotic prescriptions per 1000 65+ patient visits

Secondary

MeasureTime frameDescription
Proportion Antibiotic Rx with Prolonged Duration6 monthsAntibiotics prescribed for more than 7 days per episode
Antibiotic drug costs6 monthsCost in CDN$
Antibiotics prescribed for viral infections6 monthsTotal number of antibiotic rx per 1000 65+ patient visits for presumed viral condition (and thus likely unnecessary) based on administrative database diagnostic codes
Total Antibiotic Days of Therapy6 monthsTotal number DOTs per 1000 65+ patient visits
Proportion of broad spectrum antibiotic prescriptions6 monthsantibiotic prescriptions that are broad spectrum

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026