Covid19, Vaccination Reaction
Conditions
Brief summary
The study aims to summarize kidney histopathological findings in patients with coronavirus disease 2019 (COVID-19) and post-severe acute respiratory syndrome-coronavirus-type 2 (SARS-CoV-2) vaccination.
Detailed description
The SARS-CoV-2 pandemic has had substantial global morbidity and mortality. While COVID-19 is most commonly characterized as a respiratory illness, extrapulmonary manifestations are a prominent part its clinical spectrum. Kidney disease is a common finding in COVID-19, and has also been rarely described after SARS-CoV-2 vaccination. The main objective of this study is to summarize kidney histopathological findings in patients with COVID-19 and post-SARS-COV-2 vaccination, in whom native kidney biopsy was performed and samples were obtained by the Nephropathology Section, Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Interventions
None listed
Sponsors
Universitätsklinikum Hamburg-Eppendorf
University of Giessen
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* being diagnosed with COVID-19 when kidney biopsy was performed * history of recent homologous or heterogenous vaccine regimen comprising either vector-based vaccines or messenger ribonucleic acid-based vaccines
Exclusion criteria
* Patient refuses participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of histopathologically confirmed glomerular and tubulointerstitial diseases | Kidney biopsy obtained during COVID-19 disease and up to 3 months after SARS-CoV-2 vaccination |
Countries
Germany
Outcome results
None listed